Pineal Gland Tumors: A Review
| Autor: | Gaia Favero, Rita Rezzani, Francesca Bonomini |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Cancer Research
Pathology medicine.medical_specialty endocrine system Pineal region pineal gland Review lcsh:RC254-282 03 medical and health sciences Pineal gland 0302 clinical medicine pineal germ cell tumors Medicine Clinical significance pineal metastasis brain neoplasms business.industry medicine.disease lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens pineal parenchymal tumor medicine.anatomical_structure Oncology nervous system Pediatric brain 030220 oncology & carcinogenesis Gross anatomy Functional significance Pinealoma business 030217 neurology & neurosurgery hormones hormone substitutes and hormone antagonists Endocrine gland |
| Zdroj: | Cancers, Vol 13, Iss 1547, p 1547 (2021) Cancers |
| Popis: | Simple Summary Pineal neoplasms are tumors with different and variable morphological, histological, and radiological characteristics and, consequently different diagnosis and management. Due to their rarity, pineal tumors may be misdiagnosed. Pineal tumors, are divided into germ cell tumors, pineal parenchymal tumors and tumors that derive from adjacent structures. In this review, we report the clinical relevance of the main pineal gland tumors, underlining the importance of studying the triggering causes of pineal region carcinogenesis, to realize appropriate diagnosis and, consequently, better clinical management. Abstract The pineal gland is a small, pinecone-shaped endocrine gland that participates in the biological rhythm regulation of vertebrates. The recognized major product of the pineal gland is melatonin—a multifunctional endogenous indoleamine. Accumulating evidence suggests that the pineal gland is important for preserving ideal health conditions in vertebrate. Tumors of the pineal region account for approximately 3–11% of pediatric brain neoplasms but fewer than 1% of brain neoplasms in adults. It is fundamental to expand advanced imaging techniques together with both clinical and laboratory knowledge, to help to differentiate among pineal neoplasms and thus facilitate accurate primary diagnoses and proper therapeutic interventions. In this review, we report the gross anatomy of the pineal gland and its functional significance and discuss the clinical relevance of pineal gland tumors, underlining the importance of identifying the leading causes of pineal region masses. |
| Databáze: | OpenAIRE |
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