New Generation of Ultrasensitive Label-Free Optical Si Nanowire-Based Biosensors
| Autor: | Alessia Irrera 1, Antonio Alessio Leonardi 1, 2, 3, 4, Cinzia Di Franco 5, Maria José Lo Faro 1, Gerardo Palazzo 6, Cristiano D'Andrea 1, 7, Kyriaki Manoli 5, Giorgia Franzo 3, Paolo Musumeci 2, Barbara fazio 1, Luisa Torsi 6, Francesco Priolo 2, 8 |
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| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Analyte Photoluminescence Materials science Silicon Nanowire chemistry.chemical_element Nanotechnology 02 engineering and technology biosensor C-reactive protein nanowires photoluminescence silicon Electronic Optical and Magnetic Materials Biotechnology Atomic and Molecular Physics and Optics Electrical and Electronic Engineering 03 medical and health sciences Atomic and Molecular Physics Electronic Optical and Magnetic Materials Detection limit Dynamic range 021001 nanoscience & nanotechnology 030104 developmental biology chemistry and Optics 0210 nano-technology Luminescence Biosensor |
| Zdroj: | ACS photonics 5 (2018): 471–479. doi:10.1021/acsphotonics.7b00983 info:cnr-pdr/source/autori:Alessia Irrera 1, Antonio Alessio Leonardi 1,2,3,4, Cinzia Di Franco 5, Maria José Lo Faro 1, Gerardo Palazzo 6, Cristiano D'Andrea 1,7, Kyriaki Manoli 5, Giorgia Franzo 3, Paolo Musumeci 2, Barbara fazio 1, Luisa Torsi 6, Francesco Priolo 2,3,8/titolo:New generation of ultrasensitive label-free optical Si nanowire-based biosensors/doi:10.1021%2Facsphotonics.7b00983/rivista:ACS photonics/anno:2018/pagina_da:471/pagina_a:479/intervallo_pagine:471–479/volume:5 |
| ISSN: | 2330-4022 |
| DOI: | 10.1021/acsphotonics.7b00983 |
| Popis: | We demonstrate the realization of the first label-free optical biosensor based on the room temperature luminescence of silicon nanowires (NWs) tested for the selective detection of C- reactive protein in human serum. High aspect ratio Si NW arrays used as sensing interface, are synthesized by a fast, low-cost and Si industrially compatible approach. Si NW optical biosensors are fast and offer a broad concentration dynamic range that can be tuned according to different applications. Moreover, the platform is endowed with a high selectivity towards the target analyte and a sensitivity down to the fM limit of detection, opening the route towards non-invasive analysis in bio-fluids such as saliva. |
| Databáze: | OpenAIRE |
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