The validation of threshold decision ruls and calculator for APhiG algoritm for clarification of prostate cancer staging before treatment
| Autor: | K. M. Nushko, T. E. Skachkova, M. R. Nazirov, I. M. Shevchuk, B. Ya. Alekseev, N. V. Marshutina, V. G. Gitis, Sergey Pirogov, E. F. Yurkov, Andrey Kaprin, N. S. Sergeeva |
|---|---|
| Jazyk: | ruština |
| Rok vydání: | 2020 |
| Předmět: |
validation
medicine.medical_specialty business.industry Urology 030232 urology & nephrology aphig algorithm prostate cancer law.invention 03 medical and health sciences 0302 clinical medicine Oncology Calculator Nephrology law 030220 oncology & carcinogenesis Medicine Radiology Nuclear Medicine and imaging Surgery Medical physics staging before treatment Prostate cancer staging business |
| Zdroj: | Onkourologiâ, Vol 16, Iss 1, Pp 43-53 (2020) |
| ISSN: | 1996-1812 1726-9776 |
| Popis: | Background. We have previously described an algorithm APhiG (Age of patients, Prostate health index and Gleason score), for staging of prostate cancer before treatment. The algorithm was developed by logistic regression on a training dataset and validated on a validation dataset (VD). Objective. Validation of threshold decision rules and a program for APhiG calculation on the VD.Materials and methods. ROC curve analysis on VD (83 cases).Results and conclusion. It was shown that sensitivity, specificity, positive and negative predictive value, diagnostic accuracy threshold decision rules and area under the curve (AUC) for APhiG in the VD (n = 83) not significantly different from those indicators in the training dataset (n = 337), which was the basis for the algorithm APhiG development. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|