Inactivation of Bacillus anthracis spores to decontaminate subway railcar and related materials via the fogging of peracetic acid and hydrogen peroxide sporicidal liquids
| Autor: | Joseph P. Wood, James V. Rogers, William R. Richter, Morgan Q. S. Wendling |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Environmental Engineering Fogging 030106 microbiology 030501 epidemiology Management Monitoring Policy and Law Endospore Article Microbiology 03 medical and health sciences chemistry.chemical_compound Peracetic acid Peracetic Acid Hydrogen peroxide Railroads Waste Management and Disposal Decontamination Spores Bacterial biology Hydrogen Peroxide General Medicine Human decontamination biology.organism_classification Spore Bacillus anthracis chemistry Bacillus atrophaeus 0305 other medical science Disinfectants Nuclear chemistry |
| Zdroj: | Journal of Environmental Management. 206:800-806 |
| ISSN: | 0301-4797 |
| Popis: | The inactivation of Bacillus anthracis spores on subway and used subway railcar materials was evaluated using fogged peracetic acid/hydrogen peroxide (PAA) and hydrogen peroxide (H 2 O 2 ). A total of 21 separate decontamination tests were conducted using bacterial spores of both B. anthracis Ames ( B.a. ) and Bacillus atrophaeus ( B.g. ) inoculated onto several types of materials. Tests were conducted using commercial off-the-shelf fogging equipment filled with either PAA or H 2 O 2 to fumigate a ∼15 cubic meter chamber under uncontrolled ambient relative humidity and controlled temperature (10 or 20 °C) from 8 to 168 h. For the present study, no conditions were found that resulted in complete inactivation of either B.a. Ames or B.g. on all test materials. Approximately 41% and 38% of the decontamination efficacies for B.a. and B.g. , respectively, exhibited ≥6 log 10 reduction (LR); efficacy depended greatly on the material. When testing at 10 °C, the mean LR was consistently lower for both B.a. and B.g. as compared to 20 °C. Based on the statistical comparison of the LR results, B.g. exhibited equivalent or greater resistance than B.a. for approximately 92% of the time across all 21 tests. The efficacy data suggest that B.g. may be a suitable surrogate for B.a. Ames when assessing the decontamination efficacy of fogged PAA or H 2 O 2 . Moreover, the results of this testing indicate that in the event of B.a. spore release into a subway system, the fogging of PAA or H 2 O 2 represents a decontamination option for consideration. |
| Databáze: | OpenAIRE |
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