Additional Intestinal Mucosal Biopsy Sampling for Research Is Safe During Pediatric Endoscopic Procedures
| Autor: | Harland S. Winter, Jess L. Kaplan, Christopher J. Moran, Julia Noreck, Emma Li, Esther J. Israel, Jeffrey A. Biller |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
Hepatology business.industry Biopsy Gastroenterology Endoscopy Mucosal Biopsy medicine.disease Colitis Inflammatory Bowel Diseases Inflammatory bowel disease Additional research 03 medical and health sciences Underserved Population 0302 clinical medicine 030220 oncology & carcinogenesis medicine Humans 030211 gastroenterology & hepatology Sampling (medicine) Intestinal Mucosa Intensive care medicine business Child |
| Zdroj: | Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association. 18(5) |
| ISSN: | 1542-7714 |
| Popis: | Advancing the understanding of inflammatory bowel disease (IBD) pathogenesis has been facilitated by mechanistic studies that require human intestinal tissue. Enrolling pediatric subjects into these studies improves our knowledge of IBD in this underserved population. Given the additional research protections granted to children, institutional review boards (IRBs) must weigh the benefit of obtaining research biopsies against perceived risks. Although obtaining clinical biopsies from children is generally considered safe, there are only limited data on the safety of obtaining research biopsies in children.1-6. |
| Databáze: | OpenAIRE |
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