A Versatile Catalyst for the Sonogashira Coupling of Aryl Chlorides
Autor: | Thomas Pullmann, Axel Koellhofer, Herbert Plenio |
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Rok vydání: | 2003 |
Předmět: | |
Zdroj: | Angewandte Chemie International Edition. 42:1056-1058 |
ISSN: | 1521-3773 1433-7851 |
DOI: | 10.1002/anie.200390273 |
Popis: | Whereasarylbromidesandaryliodidesarewellknowntoundergo this reaction in the presence of suitable catalysts,thereisnoefficientprotocolfortheSonogashiracouplingofalkynes with aryl chlorides, which would be the mostattractive starting materials because of the wide variety ofcheaply available derivatives. There are a few examples ofSonogashirareactionswithalkynesandactivatedarylchlor-ides |
Databáze: | OpenAIRE |
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