A Versatile Catalyst for the Sonogashira Coupling of Aryl Chlorides

Autor: Thomas Pullmann, Axel Koellhofer, Herbert Plenio
Rok vydání: 2003
Předmět:
Zdroj: Angewandte Chemie International Edition. 42:1056-1058
ISSN: 1521-3773
1433-7851
DOI: 10.1002/anie.200390273
Popis: Whereasarylbromidesandaryliodidesarewellknowntoundergo this reaction in the presence of suitable catalysts,thereisnoefficientprotocolfortheSonogashiracouplingofalkynes with aryl chlorides, which would be the mostattractive starting materials because of the wide variety ofcheaply available derivatives. There are a few examples ofSonogashirareactionswithalkynesandactivatedarylchlor-ides
Databáze: OpenAIRE