Green approach for synthesis of gold nanoparticles from Nigella arvensis leaf extract and evaluation of their antibacterial, antioxidant, cytotoxicity and catalytic activities
| Autor: | Azam Chahardoli, Fatemeh Sadeghi, Ali Fattahi, Naser Karimi |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Antioxidant
Stereochemistry medicine.medical_treatment Biomedical Engineering Drug Evaluation Preclinical Pharmaceutical Science Medicine (miscellaneous) Metal Nanoparticles 02 engineering and technology 010402 general chemistry 01 natural sciences Antioxidants Catalysis Nigella arvensis medicine Humans Cytotoxicity Nigella Chemistry Cytotoxins General Medicine 021001 nanoscience & nanotechnology 0104 chemical sciences Anti-Bacterial Agents Colloidal gold MCF-7 Cells Gold 0210 nano-technology Biotechnology Nuclear chemistry |
| Zdroj: | Artificial cells, nanomedicine, and biotechnology. 46(3) |
| ISSN: | 2169-141X |
| Popis: | In the present work, we studied the reduction of gold ions into gold nanoparticles using Nigella arvensis leaf extract in the one-step green synthesis method. The formation of N. arvensis gold nanoparticles (NA-GNPs) was confirmed by UV-Vis spectroscopy, XRD, FT-IR and TEM analyses. The XRD pattern confirmed the crystal structure of NA-GNPs, and TEM image showed the small size (3-37 nm) and almost spherical shape of NA-GNPs. NA-GNPs have not shown enhanced antioxidant properties compared to the plant extract while they were active against the clinical isolated bacterial strains. These nanoparticles showed the cytotoxicity effects against H1299 and MCF-7 cancer cell lines with an IC |
| Databáze: | OpenAIRE |
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