Long-term survival after allogeneic bone marrow transplantation complicated by trichosporosis
Autor: | D Weinbaum, S R Petursson, C S Rosenfeld, S Naum |
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Rok vydání: | 1994 |
Předmět: |
Acute promyelocytic leukemia
Adult Male medicine.medical_specialty Antifungal Agents Neutropenia medicine.medical_treatment Antineoplastic Agents Gastroenterology Leukemia Promyelocytic Acute Trichosporon hemic and lymphatic diseases Internal medicine medicine Humans Survivors Bone Marrow Transplantation Immunosuppression Therapy Mitoxantrone business.industry Induction chemotherapy Immunosuppression General Medicine medicine.disease Transplantation Leukemia Mycoses business Fluconazole medicine.drug |
Zdroj: | Southern medical journal. 87(2) |
ISSN: | 0038-4348 |
Popis: | We report a case of sepsis due to Trichosporon cutaneum in a 20-year-old patient with acute promyelocytic leukemia. Neutropenia with a hypocellular marrow persisted for 90 days after two courses of induction chemotherapy with mitoxantrone and ara-C. Amphotericin B, fluconazole, and granulocyte-macrophage colony-stimulating factors were administered. Neutropenia (ANC < 1,000/microL) resolved 14 days after HLA-identical bone marrow transplantation. The patient is in remission, with a performance status of 100%, more than 1 year after transplantation. |
Databáze: | OpenAIRE |
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