Efficacy and reproducibility of attenuation-compensated optical coherence tomography for assessing external elastic membrane border and plaque composition in native and stented segments: an in vivo and histology-based study
| Autor: | Rajiv Amersey, Christos V. Bourantas, Anantharaman Ramasamy, Patrick W. Serruys, Thomas W Johnson, Simon Scoltock, Ryo Torii, Nicolas Foin, Stephen J. White, Michael J A Girard, Jouke Dijkstra, Andreas Baumbach, Chongying Jin, Sudheer Koganti, Tom Crake, Jaryl Ng, Daniel A. Jones, Roby Rakhit, Lorenz Räber, Anthony Mathur |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Male
Neointima genetic structures Coronary Artery Disease 030204 cardiovascular system & hematology 03 medical and health sciences 0302 clinical medicine Optical coherence tomography In vivo Humans Medicine 030212 general & internal medicine Aged Reproducibility medicine.diagnostic_test business.industry Plaque composition Attenuation External Elastic Membrane Histology General Medicine Middle Aged Coronary Vessels Plaque Atherosclerotic eye diseases Female sense organs Cardiology and Cardiovascular Medicine business Tomography Optical Coherence Biomedical engineering |
| Zdroj: | Circulation Journal, 84(1), 91-+. Japanese Circulation Society |
| Popis: | BACKGROUND:Attenuation-compensated (AC) technique was recently introduced to improve the plaque characterization of optical coherence tomography (OCT). Histological validation demonstrated promising results but the efficacy and reproducibility of this technique for assessing in-vivo tissue composition remains unclear.Methods and Results:OCT images portraying native (n=200) and stented (n=200) segments and 31 histological cross-sections were analyzed. AC-OCT appeared superior to conventional (C)-OCT in detecting the external elastic lamina (EEM) borders (76% vs. 65.5%); AC-OCT enabled larger EEM arc detection compared with C-OCT (174.2±58.7° vs. 137.5±57.9°; P |
| Databáze: | OpenAIRE |
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