Evaluation of deep learning detection and classification towards computer-aided diagnosis of breast lesions in digital X-ray mammograms
| Autor: | Seung Moo Han, Tae-Seong Kim, Mugahed A. Al-antari |
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| Rok vydání: | 2020 |
| Předmět: |
Computer science
Breast lesion Breast Neoplasms Health Informatics 030218 nuclear medicine & medical imaging Machine Learning 03 medical and health sciences Deep Learning 0302 clinical medicine Breast cancer medicine Humans Computers business.industry X-Rays Deep learning Detector Pattern recognition medicine.disease Computer Science Applications Computer-aided diagnosis Neural Networks Computer Artificial intelligence business 030217 neurology & neurosurgery Software Mammography |
| Zdroj: | Computer Methods and Programs in Biomedicine. 196:105584 |
| ISSN: | 0169-2607 |
| Popis: | Background and objective Deep learning detection and classification from medical imagery are key components for computer-aided diagnosis (CAD) systems to efficiently support physicians leading to an accurate diagnosis of breast lesions. Methods In this study, an integrated CAD system of deep learning detection and classification is proposed aiming to improve the diagnostic performance of breast lesions. First, a deep learning YOLO detector is adopted and evaluated for breast lesion detection from entire mammograms. Then, three deep learning classifiers, namely regular feedforward CNN, ResNet-50, and InceptionResNet-V2, are modified and evaluated for breast lesion classification. The proposed deep learning system is evaluated over 5-fold cross-validation tests using two different and widely used databases of digital X-ray mammograms: DDSM and INbreast. Results The evaluation results of breast lesion detection show the capability of the YOLO detector to achieve overall detection accuracies of 99.17% and 97.27% and F1-scores of 99.28% and 98.02% for DDSM and INbreast datasets, respectively. Meanwhile, the YOLO detector could predict 71 frames per second (FPS) at the testing time for both DDSM and INbreast datasets. Using detected breast lesions, the classification models of CNN, ResNet-50, and InceptionResNet-V2 achieve promising average overall accuracies of 94.50%, 95.83%, and 97.50%, respectively, for the DDSM dataset and 88.74%, 92.55%, and 95.32%, respectively, for the INbreast dataset. Conclusion The capability of the YOLO detector boosted the classification models to achieve a promising breast lesion diagnostic performance. Such prediction results should help to develop a feasible CAD system for practical breast cancer diagnosis. |
| Databáze: | OpenAIRE |
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