A Rare Case of Subacute Sclerosing Panencephalitis Presenting As Generalized Seizure
| Autor: | Nabin Simkhada, Prakash Adhikari, Krish Mahat, Bishnu Deep Pathak, Bishal Dhakal |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Pediatrics
medicine.medical_specialty Weakness Urinary incontinence subacute sclerosing panencephalitis 030204 cardiovascular system & hematology Electroencephalography Fluid-attenuated inversion recovery Measles Subacute sclerosing panencephalitis adult onset sspe 03 medical and health sciences 0302 clinical medicine sspe Internal Medicine Medicine medicine.diagnostic_test business.industry Generalized seizure General Engineering medicine.disease Neurology medicine.symptom business Complication measles complication 030217 neurology & neurosurgery measles virus infection |
| Zdroj: | Cureus |
| ISSN: | 2168-8184 |
| Popis: | Subacute sclerosing panencephalitis (SSPE) is a late complication of childhood measles. It is characterized by a progressive decline in cognitive and motor functions, seizures, and eventually death. Although a combination of intrathecal interferon alpha (IFN-α) and daily oral isoprinosine has been reported to have a good outcome, there is no cure for this condition. We present a case of a 16-year-old male with SSPE who presented with progressive weakness, frequent loss of postural control, multiple episodes of generalized tonic-clonic seizures, and urinary incontinence. On exploration of his history, he had measles at the age of two months. Investigation showed increased serum measles antibody titer, high amplitude spikes in electroencephalogram (EEG), and high fluid-attenuated inversion recovery (FLAIR) signals on MRI of the brain consistent with probable SSPE. He was managed symptomatically until his condition got worse and he eventually passed away. |
| Databáze: | OpenAIRE |
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