Risk factors for the development of hip osteoarthritis: a population-based prospective study
| Autor: | O Impivaara, Jari Arokoski, Markku Heliovaara, Heikki Kröger, H. Lauren, Paul Knekt, R. Juhakoski |
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| Rok vydání: | 2008 |
| Předmět: |
Adult
Male medicine.medical_specialty Physical Exertion Physical examination Workload Osteoarthritis Hip Age Distribution Rheumatology Internal medicine Arthropathy medicine Humans Pharmacology (medical) Risk factor Prospective cohort study Musculoskeletal System Finland Aged Aged 80 and over medicine.diagnostic_test business.industry Odds ratio Middle Aged medicine.disease Occupational Diseases Musculoskeletal injury Physical therapy Wounds and Injuries Population study Female Epidemiologic Methods business |
| Zdroj: | Rheumatology. 48:83-87 |
| ISSN: | 1462-0332 1462-0324 |
| Popis: | Objectives Potential risk factors and their roles in the aetiology of hip OA are poorly understood. We analysed several alleged risk factors predisposing to hip OA in a 22-yr prospective study. Methods A comprehensive health survey was carried out in 1978-80 in a nationally representative sample of adult Finns. In 2000-01, 1286 participants in that survey were invited for re-examination, and 909 agreed to participate. After excluding those with hip OA at the baseline and those who were no longer working, a total of 840 subjects constituted the present study population. Hip OA was diagnosed on the basis of a standardized clinical examination by physicians who applied uniform criteria both at the baseline and at the re-examination phase. Results After 22 yrs of follow-up, hip OA was diagnosed in 41 subjects (4.9%). Heavy manual labour predicted the risk of developing hip OA [adjusted odds ratio (OR) 6.7; 95% CI 2.3, 19.5]. Permanent damage as a consequence of any musculoskeletal injury was also an independent predictor of hip OA (adjusted OR 5.0; 95% CI 1.9, 13.3). BMI, smoking, alcohol intake and leisure time physical activity were not factors which were predictive for hip OA. Conclusion Heavy physical stress at work and major musculoskeletal injuries are associated with an increased risk of developing clinically diagnosed hip OA. |
| Databáze: | OpenAIRE |
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