Carcinoma cuniculatum of the larynx
Autor: | Antonio Greco, Giacomo D’Angeli, Marco de Vincentiis, Massimo Ralli, Mara Riminucci, Daniela Messineo, Alessandro Corsi, Federica Zoccali, Antonio Gilardi, Dario Marcotullio |
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Jazyk: | angličtina |
Rok vydání: | 2021 |
Předmět: |
0301 basic medicine
Larynx Male medicine.medical_specialty Pathology Contrast Media Case Reports Pathology and Forensic Medicine Diagnosis Differential 03 medical and health sciences 0302 clinical medicine medicine Left vocal cord Carcinoma Humans Radical surgery Laryngeal Neoplasms Smokers Laryngoscopy Verrucous carcinoma business.industry Middle Aged medicine.disease 030104 developmental biology medicine.anatomical_structure Oncology Otorhinolaryngology Invasive growth 030220 oncology & carcinogenesis carcinoma cuniculatum histological diagnosis larynx upper aero-digestive tract verrucous carcinoma vocal cords well-differentiated squamous cell carcinoma Oral and maxillofacial surgery Carcinoma Squamous Cell business Tomography X-Ray Computed |
Zdroj: | Head Neck Pathol |
Popis: | Carcinoma cuniculatum (CC) is a rare clinicopathologic variant of squamous cell carcinoma. Histologically, it is characterized by invasive growth of bland, acanthotic, and keratinizing squamous epithelium that forms multiple rabbit burrow-like, keratin-filled crypts and sinuses. We present a 51-year-old male smoker with CC of the left vocal cord. The tumor was staged T1a and the patient was disease-free 12 months after surgery. To our knowledge, this is the fourth case of CC of the larynx reported in the English literature and the first, due to its early diagnosis, where radical surgery was not performed. We highlight the necessity for awareness of this entity and coordination between otolaryngologists, radiologists, and pathologists for early diagnosis and organ-sparing surgical treatment. |
Databáze: | OpenAIRE |
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