Influence of caffeine on blood pressure and platelet aggregation
| Autor: | Marcus G. F. de Menezes, José Wilson S. Cavalcante, Walewska S. Pacheco, Leonardo Pessoa Cavalcante, Hedylamar Oliveira Marques, Paulo Roberto M. Santos |
|---|---|
| Rok vydání: | 2000 |
| Předmět: |
Adult
Male medicine.medical_specialty lcsh:Diseases of the circulatory (Cardiovascular) system Platelet aggregation Platelet Aggregation Phosphodiesterase Inhibitors Blood Pressure chemistry.chemical_compound Internal medicine Caffeine medicine Humans Platelet Young adult caffeine Analysis of Variance business.industry blood pressure Adenosine Adenosine receptor Adenosine diphosphate Endocrinology Blood pressure chemistry Purinergic P1 Receptor Antagonists lcsh:RC666-701 adenosine Anesthesia Hypertension Central Nervous System Stimulants Female Cardiology and Cardiovascular Medicine business medicine.drug |
| Zdroj: | Arquivos Brasileiros de Cardiologia v.75 n.2 2000 Arquivos Brasileiros de Cardiologia Sociedade Brasileira de Cardiologia (SBC) instacron:SBC Arquivos Brasileiros de Cardiologia, Vol 75, Iss 2, Pp 102-105 (2000) Arquivos Brasileiros de Cardiologia, Volume: 75, Issue: 2, Pages: 102-105, Published: AUG 2000 |
| ISSN: | 0066-782X |
| Popis: | OBJECTIVE: Studies have demonstrated that methylxanthines, such as caffeine, are A1 and A2 adenosine receptor antagonists found in the brain, heart, lungs, peripheral vessels, and platelets. Considering the high consumption of products with caffeine in their composition, in Brazil and throughout the rest of the world, the authors proposed to observe the effects of this substance on blood pressure and platelet aggregation. METHODS: Thirteen young adults, ranging from 21 to 27 years of age, participated in this study. Each individual took 750mg/day of caffeine (250mg tid), over a period of seven days. The effects on blood pressure were analyzed through the pressor test with handgrip, and platelet aggregation was analyzed using adenosine diphosphate, collagen, and adrenaline. RESULTS: Diastolic pressure showed a significant increase 24 hours after the first intake (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|