Cigarette Smoking and Subclinical Peripheral Arterial Disease in Blacks of the Jackson Heart Study

Autor: Andrew P. DeFilippis, Michael E. Hall, Kenneth R. Butler, Adolfo Correa, Daisuke Kamimura, Aruni Bhatnagar, Javed Butler, Michael J. Blaha, Loretta Cain, Wendy B. White, Rose Marie Robertson, Emelia J. Benjamin, Robert J. Mentz, Donald Clark
Rok vydání: 2019
Předmět:
Male
Epidemiology
Arterial disease
medicine.medical_treatment
Disease
030204 cardiovascular system & hematology
Mississippi
0302 clinical medicine
Risk Factors
Prevalence
Medicine
Longitudinal Studies
Prospective Studies
030212 general & internal medicine
Original Research
Subclinical infection
Aged
80 and over
education.field_of_study
Middle Aged
3. Good health
Peripheral
Cohort
Female
Cardiology and Cardiovascular Medicine
Adult
Race and Ethnicity
medicine.medical_specialty
Population
peripheral artery disease
Risk Assessment
smoking
Cigarette Smoking
Peripheral Arterial Disease
Young Adult
03 medical and health sciences
black
Internal medicine
Humans
Ankle Brachial Index
education
Aged
business.industry
Odds ratio
Lifestyle
Black or African American
Peripheral Vascular Disease
Smoking cessation
Smoking Cessation
Self Report
business
Follow-Up Studies
Zdroj: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
ISSN: 2047-9980
DOI: 10.1161/jaha.118.010674
Popis: Background Prevalence of peripheral artery disease ( PAD ) is significantly higher among blacks as compared with non‐Hispanic whites, but the role of cigarette smoking in PAD is understudied in blacks. We aimed to evaluate the relationship between cigarette smoking and PAD in blacks in the (JHS) Jackson Heart Study. Methods and Results JHS participants (n=5306) were classified by self‐reported baseline smoking status into current, past (smoked at least 400 cigarettes/life), or never smokers. We examined multivariable logistic and robust linear regression models to estimate the associations between baseline smoking status, smoking intensity, and measures of subclinical PAD (ankle‐brachial index [visit 1] and aortic calcium by computed tomography [visit 2]) to yield odds ratios and β‐coefficients (estimated adjusted difference) to compare each smoking status with never smokers (reference group). There were 3579 (68%) never smokers, 986 (19%) past smokers, and 693 (13%) current smokers self‐identified at baseline. After adjustment for covariates, current smokers had increased risk of ankle‐brachial index PAD by all of these measures compared with lower‐intensity use, suggesting a dose‐dependent relationship. Conclusions In a large black cohort, cigarette smoking was associated with measures of subclinical PAD in a dose‐dependent manner. These findings highlight the association between smoking and PAD in blacks and support further research exploring the impact of interventions on smoking cessation to reduce PAD in this population.
Databáze: OpenAIRE
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