Downstream Targets of Cyclic Nucleotides in Plants
| Autor: | Maria Duszyn, Adriana Szmidt-Jaworska, Krzysztof Jaworski, Brygida Świeżawska |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
0106 biological sciences
0301 basic medicine Mini Review Plant Science Biology lcsh:Plant culture 01 natural sciences 03 medical and health sciences Cyclic nucleotide chemistry.chemical_compound cyclic GMP Nucleotide lcsh:SB1-1110 cyclic AMP phosphodiesterases Protein kinase A cNMP-dependent protein kinases chemistry.chemical_classification Kinase Effector plants Phosphodiesterase cyclic nucleotide effectors Cell biology 030104 developmental biology chemistry Signal transduction signaling Function (biology) 010606 plant biology & botany |
| Zdroj: | Frontiers in Plant Science Frontiers in Plant Science, Vol 9 (2018) |
| ISSN: | 1664-462X |
| Popis: | Efficient integration of various external and internal signals is required to maintain adaptive cellular function. Numerous distinct signal transduction systems have evolved to allow cells to receive these inputs, to translate their codes and, subsequently, to expand and integrate their meanings. Two of these, cyclic AMP and cyclic GMP, together referred to as the cyclic nucleotide signaling system, are between them. The cyclic nucleotides regulate a vast number of processes in almost all living organisms. Once synthesized by adenylyl or guanylyl cyclases, cyclic nucleotides transduce signals by acting through a number of cellular effectors. Because the activities of several of these effectors are altered simultaneously in response to temporal changes in cyclic nucleotide levels, agents that increase cAMP/cGMP levels can trigger multiple signaling events that markedly affect numerous cellular functions. In this mini review, we summarize recent evidence supporting the existence of cNMP effectors in plant cells. Specifically, we highlight cAMP-dependent protein kinase A (PKA), cGMP-dependent kinase G (PKG), and cyclic nucleotide phosphodiesterases (PDEs). Essentially this manuscript documents the progress that has been achieved in recent decades in improving our understanding of the regulation and function of cNMPs in plants and emphasizes the current gaps and unanswered questions in this field of plant signaling research. |
| Databáze: | OpenAIRE |
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