Behavioural and demographic correlates of undiagnosed HIV infection in a MSM sample recruited in 13 European cities
| Autor: | Cinta Folch, Emilia Naseva, Massimo Mirandola, Reneta Dimitrova, Lorenzo Gios, Maria Nikolova, Sónia Dias, Hristo Taskov, João Piedade, Oscar Bortolami, Susanne Barbara Schink, Ricardo Fuertes, Daniela Pitigoi, Ulrich Marcus, Thierry Martin, Matthias An der Heiden, ANA FILIPA GAMA, Miguel Rocha, Lukasz Henszel, Ivailo Alexiev, Tonka Varleva, Sandra Dudareva, Nigel Sherriff, Magdalena Rosińska, BARBARA SULIGOI, Lucia Pugliese, Vincenza Regine |
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| Přispěvatelé: | Escola Nacional de Saúde Pública (ENSP), Centro de Investigação em Saúde Pública (CISP/PHRC), Instituto de Higiene e Medicina Tropical (IHMT) |
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Male
Human immunodeficiency virus (HIV) HIV Infections medicine.disease_cause Men who have sex with men Sexual and Gender Minorities Biobehavioural survey Europe HIV Men having sex with men Undiagnosed HIV infection 0302 clinical medicine Medical microbiology 030212 general & internal medicine virus diseases Middle Aged Sexual Partners Infectious Diseases 0305 other medical science Research Article Adult medicine.medical_specialty Adolescent Substance-Related Disorders Sexual Behavior Sexually Transmitted Diseases Hiv testing Odds lcsh:Infectious and parasitic diseases Young Adult 03 medical and health sciences SDG 3 - Good Health and Well-being medicine Humans lcsh:RC109-216 ddc:610 Cities Homosexuality Male Aged 030505 public health business.industry Odds ratio Confidence interval Cross-Sectional Studies Socioeconomic Factors Tropical medicine business 610 Medizin und Gesundheit Demography |
| Zdroj: | Repositório Científico de Acesso Aberto de Portugal Repositório Científico de Acesso Aberto de Portugal (RCAAP) instacron:RCAAP BASE-Bielefeld Academic Search Engine BMC Infectious Diseases, Vol 18, Iss 1, Pp 1-15 (2018) BMC Infectious Diseases |
| Popis: | Background Reducing the number of people with undiagnosed HIV infection is a major goal of HIV control and prevention efforts in Europe and elsewhere. We analysed data from a large multi-city European bio-behavioural survey conducted among Men who have Sex with Men (MSM) for previously undiagnosed HIV infections, and aimed to characterise undiagnosed MSM who test less frequently than recommended. Methods Data on sexual behaviours and social characteristics of MSM with undiagnosed HIV infection from Sialon II, a bio-behavioural cross-sectional survey conducted in 13 European cities in 2013/2014, were compared with HIV-negative MSM. Based on reported HIV-testing patterns, we distinguished two subgroups: MSM with a negative HIV test result within 12 months prior to the study, i.e. undiagnosed incident infection, and HIV positive MSM with unknown onset of infection. Bivariate and multivariate associations of explanatory variables were analysed. Distinct multivariate multi-level random-intercept models were estimated for the entire group and both subgroups. Results Among 497 participants with HIV-reactive specimens, 234 (47.1%) were classified as previously diagnosed, 106 (21.3%) as incident, and 58 (11.7%) as unknown onset based on self-reported status and testing history. MSM with incident HIV infection were twice as likely (odds ratio (OR) = 2.22, 95% confidence interval (95%CI): 1.17–4.21) to have used recreational substances during their last anal sex encounter and four times more likely (OR = 3.94, 95%CI: 2.14–7.27) not to discuss their HIV status with the last anal sex partner(s). MSM with unknown onset of HIV infection were 3.6 times more likely (OR = 3.61, 95%CI: 1.74–7.50) to report testing for a sexually transmitted infection (STI) during the last 12 months. Conclusions Approximately one third of the study participants who are living with HIV were unaware of their infection. Almost two-third (65%) of those with undiagnosed HIV appeared to have acquired the infection recently, emphasizing a need for more frequent testing. Men with the identified behavioural characteristics could be considered as primary target group for HIV Pre-Exposure Prophylaxis (PrEP) to avoid HIV infection. The increased odds of those with unknown onset of HIV infection to have had an STI test in the past year strongly suggests a lost opportunity to offer HIV testing. Electronic supplementary material The online version of this article (10.1186/s12879-018-3249-8) contains supplementary material, which is available to authorized users. |
| Databáze: | OpenAIRE |
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