Prevalence of and factors associated with depression among people living with HIV in France

Autor: Jean-michel Molina, Tristan Ferry, Laure Tron, Pierre Delobel, Jean-Daniel Lelievre, Rosemary Dray-Spira, Patrizia Carrieri, Eric DENES, Victoire De Lastours, Julie BOTTERO, Bruno MARCHOU, Nicolas Lorente, Sophie Matheron, Cedric Arvieux
Přispěvatelé: Institut Pierre Louis d'Epidémiologie et de Santé Publique (iPLESP), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre de recherche en épidémiologie et santé des populations (CESP), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Université Paris-Sud - Paris 11 (UP11)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Paul Brousse-Institut National de la Santé et de la Recherche Médicale (INSERM), Sciences Economiques et Sociales de la Santé & Traitement de l'Information Médicale (SESSTIM - U912 INSERM - Aix Marseille Univ - IRD), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Observatoire régional de la santé Provence-Alpes-Côte d'Azur [Marseille] (ORS PACA), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Université Paris-Sud - Paris 11 (UP11)-Hôpital Paul Brousse-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Versailles Saint-Quentin-en-Yvelines (UVSQ), Institut de Recherche pour le Développement (IRD)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Aix Marseille Université (AMU), Observatoire Régional de la Santé PACA, ORS PACA, HAL-UPMC, Gestionnaire
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Male
0301 basic medicine
[SDV.MHEP.PSM] Life Sciences [q-bio]/Human health and pathology/Psychiatrics and mental health
HIV Infections
Men who have sex with men
0302 clinical medicine
5. Gender equality
Risk Factors
[SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases
Surveys and Questionnaires
Prevalence
Medicine
Pharmacology (medical)
030212 general & internal medicine
10. No inequality
Sida
Major depressive episode
Depression (differential diagnoses)
education.field_of_study
biology
Health Policy
Middle Aged
3. Good health
Infectious Diseases
symbols
[SDV.MHEP.MI] Life Sciences [q-bio]/Human health and pathology/Infectious diseases
Female
France
medicine.symptom
Adult
medicine.medical_specialty
Sexual Behavior
Population
Young Adult
03 medical and health sciences
symbols.namesake
Humans
Poisson regression
Psychiatry
education
Socioeconomic status
Depressive Disorder
Marital Status
business.industry
biology.organism_classification
030112 virology
Confidence interval
Logistic Models
[SDV.SPEE] Life Sciences [q-bio]/Santé publique et épidémiologie
[SDV.MHEP.PSM]Life Sciences [q-bio]/Human health and pathology/Psychiatrics and mental health
[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie
business
Demography
Zdroj: HIV Medicine
HIV Medicine, 2016, ⟨10.1111/hiv.12438⟩
HIV Medicine, Wiley, 2016, ⟨10.1111/hiv.12438⟩
ISSN: 1464-2662
1468-1293
DOI: 10.1111/hiv.12438⟩
Popis: Agence Nationale de Recherche sur le Sida et les Hépatites Virales (ANRS)-VIH: Enquête sur les personnes atteintes (Vespa2) Study Group; International audience; Objectives: Depression is common among people living with HIV (PLWHIV) and is associated with poorer therapeutic outcomes and risky behaviours. We sought to estimate the prevalence of major depressive episode (MDE) across PLWHIV groups, to compare this with its prevalence in the general population and to assess factors associated with it.Methods: We used data from the Agence Nationale de Recherche sur le Sida et les Hépatites Virales (ANRS)-Vespa2 study, a national study on a representative sample of PLWHIV conducted in France in 2011. The short form of the depression module of the World Health Organization's Composite International Diagnostic Instrument (CIDI-SF) was used to characterize the occurrence of an MDE during the previous year. MDE prevalence was assessed among the various groups of PLWHIV and compared with that in the general population, accounting for the sociodemographic characteristics of the two populations, using multivariate Poisson regression models. The same method was used to assess associated factors.Results: MDE prevalence was 28.1% among PLWHIV, ranging from 10.9 to 55.7% across groups. Compared with the general population by sex, regardless of sexual orientation and origin, MDE prevalence was 5.1-fold higher in HIV-infected men who have sex with men [95% confidence interval (CI) 3.9–6.6], 3.1-fold higher in non-sub-Saharan African (SSA) heterosexual men (95% CI 2.2–4.4), 1.6-fold higher in SSA migrant men (95% CI 0.9–2.6), 2.6-fold higher in non-SSA heterosexual women (95% CI 2.1–3.3), and 1.9-fold higher in SSA migrant women (95% CI 1.5–2.5). In the HIV-infected population, MDE was positively related to unemployment, material deprivation, disclosure, experience of discrimination, and untreated hepatitis C, and negatively related to age.Conclusions: The prevalence of depression varied across the different groups of PLWHIV, with levels much higher than in the general population. Moreover, there was a strong association with socioeconomic status and HIV experience.
Databáze: OpenAIRE
Externí odkaz: