Tropheryma whipplei intestinal colonization in Italian and migrant population: a retrospective observational study
| Autor: | Giorgio Zavarise, Francesco Doro, Francesca Perandin, Maureen Laroche, Andrea Ragusa, Sophie Edouard, Giovanni Giorli, Zeno Bisoffi, Didier Raoult, Anna Beltrame, Florence Fenollar, Fabio Formenti |
|---|---|
| Přispěvatelé: | Microbes évolution phylogénie et infections (MEPHI), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS), Vecteurs - Infections tropicales et méditerranéennes (VITROME), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut de Recherche Biomédicale des Armées (IRBA), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut de Recherche Biomédicale des Armées [Brétigny-sur-Orge] (IRBA) |
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Male
0301 basic medicine migrants Disease Feces [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases Epidemiology Europe PCR Whipple's disease epidemiology intestinal colonization Child ComputingMilieux_MISCELLANEOUS Aged 80 and over Transients and Migrants [SDV.MHEP.ME]Life Sciences [q-bio]/Human health and pathology/Emerging diseases biology Middle Aged 3. Good health Intestines Italy Child Preschool [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology Coinfection Female Whipple Disease Adult Microbiology (medical) medicine.medical_specialty Adolescent 030106 microbiology Tropheryma Microbiology Tropheryma whipplei Young Adult 03 medical and health sciences Entamoeba histolytica [SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system Internal medicine medicine Humans [SDV.MP.PAR]Life Sciences [q-bio]/Microbiology and Parasitology/Parasitology Aged Retrospective Studies business.industry Infant Retrospective cohort study medicine.disease biology.organism_classification [SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology 030104 developmental biology Observational study business |
| Zdroj: | Future Microbiology Future Microbiology, Future Medicine, 2019, 14 (4), pp.283-292. ⟨10.2217/fmb-2018-0347⟩ Future Microbiology, 2019, 14 (4), pp.283-292. ⟨10.2217/fmb-2018-0347⟩ |
| ISSN: | 1746-0913 1746-0921 |
| Popis: | Aim:To obtain the first molecular epidemiological survey of Tropheryma whipplei intestinal colonization in Italy. Materials & methods: Retrospective, observational study to assess the prevalence of T. whipplei, the causative agent of Whipple's disease, in stool samples (real-time PCR) of patients attending the Center for Tropical Diseases (Italy) and risk factors associated. Results:Overall prevalence was 6.9% (85/1240). The younger age group showed a significantly higher rate than older age group (12.7 vs 5.9%, p = 0.002). The prevalence was 4.9% for Italians and 9.3% for migrants (p = 0.003). Among the latter, children less than 10 years had higher prevalence than older ones (17.3 vs 7.3%, p = 0.003). The young age, male gender and Giardia duodenalis and Entamoeba histolytica coinfection were risk factors. Conclusion:Our study confirms an increased risk of acquiring T. whipplei infection during childhood, under poor sanitary conditions. |
| Databáze: | OpenAIRE |
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