Attaching and effacing enteropathogenic Escherichia coli as a cause of infantile diarrhea in Bangkok
| Autor: | Udom Lexomboon, Knutton S, Ida Ørskov, Echeverria P, Flemming Scheutz, Frits Ørskov, Brown Je |
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| Předmět: |
DNA
Bacterial Serotype Virulence medicine.disease_cause Microbiology Lesion Escherichia parasitic diseases Escherichia coli medicine Humans Immunology and Allergy Outpatient clinic Serotyping Enteropathogenic Escherichia coli Adhesins Escherichia coli biology Infant Newborn Infant Thailand biology.organism_classification Virology Diarrhea Infectious Diseases Case-Control Studies Diarrhea Infantile bacteria medicine.symptom Bacterial Outer Membrane Proteins |
| Zdroj: | Scopus-Elsevier |
| Popis: | To identify Escherichia coli that cause infantile diarrhea in Bangkok, Thailand, E. coli isolated in a year-long study of infantile diarrhea were examined for O and H serotypes and virulence determinants. Classic enteropathogenic E. coli (EPEC) were isolated from 28 of 509 infants with diarrhea (cases) and 11 of 509 age-matched controls (P = .009; odds ratio [OR], 2.64). Most of this difference was attributable to EPEC adherence factor (EAF)-positive EPEC that produced an attachment and effacement lesion, as identified in the fluorescence actin staining assay, isolated from 13 cases and 1 control (P = .003; OR, 13.3). EAF-EPEC was isolated from 15 cases and 10 controls (P = .418; OR, 1.52) and EAF+ non-EPEC from 17 cases and 10 controls (P = .242; OR, 1.72). EAF+EPEC that caused an attachment and effacement lesion was found in 3% of children less than 6 months old with diarrhea who were studied in an outpatient clinic in Bangkok in 1988. |
| Databáze: | OpenAIRE |
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