Better brain connectivity is associated with higher total fat mass and lower visceral adipose tissue in military pilots

Autor: David Cárdenas, Carlos de Teresa, Andrés Catena, Raimundo Jiménez, Jesús Vera, Iker Madinabeitia, Francisco Alarcón
Přispěvatelé: Universidad de Alicante. Departamento de Didáctica General y Didácticas Específicas, Research in Physical Education, Fitness and Performance (RIPEFAP)
Jazyk: angličtina
Rok vydání: 2020
Předmět:
0301 basic medicine
Adult
Male
medicine.medical_specialty
Adipose tissue
lcsh:Medicine
Overweight
Intra-Abdominal Fat
Article
White matter
03 medical and health sciences
0302 clinical medicine
Absorptiometry
Photon
Total fat mass
Internal medicine
Fractional anisotropy
medicine
Educación Física y Deportiva
Dementia
Humans
Total fat
Brain connectivity
lcsh:Science
Multidisciplinary
Military pilots
business.industry
lcsh:R
nutritional and metabolic diseases
Cognitive neuroscience
Middle Aged
medicine.disease
White Matter
Pilots
030104 developmental biology
medicine.anatomical_structure
Endocrinology
Diffusion Tensor Imaging
Military Personnel
Neurology
Visceral adipose tissue
Body Composition
Anisotropy
Female
lcsh:Q
medicine.symptom
business
Body mass index
030217 neurology & neurosurgery
Diffusion MRI
Zdroj: Digibug: Repositorio Institucional de la Universidad de Granada
Universidad de Granada (UGR)
RUA. Repositorio Institucional de la Universidad de Alicante
Universidad de Alicante (UA)
Scientific Reports, Vol 10, Iss 1, Pp 1-7 (2020)
Scientific Reports
Digibug. Repositorio Institucional de la Universidad de Granada
instname
Popis: Research by D.C., I.M., J.V. and F.A. is funded by the Spanish Ministry of Economy and Competitiveness (Agencia Estatal de Investigacion) grant DEP2017-89879-R. Also, funding was provided by CEMIX (Centro Mixto UGRMADOC, Spain) grant PIN 11. The authors are indebted to Juan F. Navas for his help in crafting the article. The authors deeply thank the collaboration of the pilots of BHELA-1, their commanders, specially LieutenantColonel Santiago Juan Fenandez Ortiz-Repiso and commander Alberto Jose Cherino Munoz, and the personnel of MADOC (Army of Spain), especially Lieutenant-Colonel Lorenzo Rebollo Gomez.
A lack of exercise leads to being overweight or obese affecting regional brain structure and functional connectivity associated with impaired cognitive function and dementia. In recent decades, several studies of healthy individuals suggest that adiposity may also produce negative independent effects on the brain. We aimed to investigate the relationship between body composition – total fat mass (TFM) and visceral adipose tissue (VAT) – with white matter (WM) integrity using a whole-brain approach in military pilots. Twenty-three military helicopter pilots (Mage = 36.79; SD = 8.00; MBMI = 25.48; SD = 2.49) took part in the study. Brain volumes were studied using diffusion tensor imaging technique by means of a 3T Magnetom Tim Trio. Measurements of body mass index (BMI), TFM and VAT were obtained using Dual-energy X-ray Absorptiometry (DXA). The results showed that, on one hand, higher TFM was associated with higher white matter fractional anisotropy (FA) and, on the other hand, higher VAT was associated with lower FA. Data showed that TFM and VAT are the critical factors underlying WM integrity in combat helicopter pilots. The authors suggest that fat presence enhance brain connectivity while there is no excess, specifically in VAT.
Spanish Ministry of Economy and Competitiveness (Agencia Estatal de Investigacion) DEP2017-89879-R
CEMIX (Centro Mixto UGRMADOC, Spain) PIN 11
Databáze: OpenAIRE
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