Clonidine Premedication Versus Placebo: Effects on Postoperative Agitation and Recovery Time in Children Undergoing Strabismus Surgery
| Autor: | Laura J. Heinmiller, Leonard B Nelson, Marc B Goldberg, Adam R Thode |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
Male
medicine.medical_specialty Time Factors Adolescent Eye Movements Premedication Placebo Clonidine law.invention Patient satisfaction Double-Blind Method Randomized controlled trial law Surveys and Questionnaires Preoperative Care Humans Medicine Prospective Studies Child Analgesics business.industry Infant Recovery of Function General Medicine medicine.disease Surgery Strabismus Ophthalmology Treatment Outcome Emergence delirium Oculomotor Muscles Patient Satisfaction Child Preschool Anesthesia Pediatrics Perinatology and Child Health Female business Pediatric anesthesia Follow-Up Studies medicine.drug Strabismus surgery |
| Zdroj: | Journal of Pediatric Ophthalmology & Strabismus. 50:150-154 |
| ISSN: | 1938-2405 0191-3913 |
| Popis: | Purpose: Postoperative agitation is common in adults and children following the use of several anesthetics, particularly inhalation anesthetics. This behavior has detrimental effects both physically for the patient following the procedure and psychologically for the parent or guardian. The authors propose that clonidine, an alpha-2 agonist, would provide a reduction in children’s postoperative agitation and, in turn, improve parent satisfaction in children undergoing strabismus surgery. Methods: Fifty children were prospectively randomized to receive either clonidine or placebo in a double-blind fashion prior to surgery. The children were evaluated using preoperative and postoperative parent questionnaires and postoperative behavioral evaluation using standardized scales including the Pediatric Anesthesia Emergence Delirium and Watcha scales. Results: Children receiving clonidine immediately after anesthesia induction had statistically significant improvement in postoperative agitation at the 15-minute mark ( P = .096) and last score obtained ( P = .095) using the Watcha scale. The clonidine group spent an insignificantly longer time in the post-anesthesia care unit (average: 54 minutes) than the placebo group (average 47 minutes) ( P = .17). Seventy-one percent of parents reported being “very satisfied” with their child’s recovery from anesthesia in the clonidine group compared to 46% in the placebo group, although this was not statistically significant ( P = .34). Conclusions: Children receiving clonidine prior to undergoing strabismus surgery have a small but noticeable reduction in postoperative agitation, stay slightly longer in the post-anesthesia care unit, and have higher rates of parent satisfaction. [J Pediatr Ophthalmol Strabismus 2013;50(3):150–154.] |
| Databáze: | OpenAIRE |
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