Coblation lesion formation in a porcine tongue model
| Autor: | Jose E. Barrera, Nathan L. Salinas |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
medicine.medical_specialty
Swine medicine.medical_treatment Sus scrofa Cryotherapy Catheter ablation Lesion formation Tongue Base Tissue Culture Techniques Tongue medicine Animals In patient business.industry Dissection Equipment Design Surgery medicine.anatomical_structure Otorhinolaryngology Models Animal Catheter Ablation business |
| Zdroj: | Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery. 143(3) |
| ISSN: | 1097-6817 |
| Popis: | To investigate, in a porcine tongue model, the lesions created by coblation to define the optimal application of this method in treating the enlarged tongue base in patients with obstructive sleep apnea syndrome.A prospective, experimental animal study.Military medical center.Fifteen fresh porcine tongue specimens were injected with normal saline, and a single coblation probe was applied to the tongue specimens to create multiple submucosal lesions at specific energy settings. Control lesions were created without the use of saline injections. After creating the lesions, the porcine tongue specimens were sectioned and examined grossly. Size and character of lesions were recorded for each of the specimens and were compared across energy settings.The energy applied at each setting was calculated on the basis of watts multiplied by treatment time. Coblation with saline injection created visible lesions with an average lesion area of 1.20 to 2.87 cm(2). The average lesion area increased as setting increased. Without saline injection, the average lesion area was 0.15 to 0.8 cm(2).The porcine tongue model describes the relationship between lesion size and cold ablation device settings. Setting, but not time, significantly affects lesion size. The coblation setting and treatment time directly impact the amount of energy delivered. Additionally, submucosal normal saline injection significantly increases lesion size at all settings and application times. Given the average lesion diameter described in this study, placing lesions 1 cm apart will optimize the area affected by coblation while minimizing lesion overlap. |
| Databáze: | OpenAIRE |
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