Resting-state functional MRI of the default mode network in epilepsy
| Autor: | Patricia Desmond, Elaine Lui, Terence J. O'Brien, Ofer M Gonen, Patrick Kwan |
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| Rok vydání: | 2020 |
| Předmět: |
Male
Rest Brain mapping 03 medical and health sciences Behavioral Neuroscience Epilepsy 0302 clinical medicine Neuroimaging medicine Humans 030212 general & internal medicine Generalized epilepsy Default mode network Brain Mapping medicine.diagnostic_test Resting state fMRI business.industry Brain Default Mode Network Magnetic resonance imaging medicine.disease Magnetic Resonance Imaging Neurology Female Neurology (clinical) Nerve Net business Functional magnetic resonance imaging human activities Neuroscience 030217 neurology & neurosurgery |
| Zdroj: | Epilepsy & Behavior. 111:107308 |
| ISSN: | 1525-5050 |
| Popis: | The default mode network (DMN) is a major neuronal network that deactivates during goal-directed tasks. Recent advances in neuroimaging have shed light on its structure and function. Alterations in the DMN are increasingly recognized in a range of neurological and psychiatric conditions including epilepsy. This review first describes the current understanding of the DMN in health, normal aging, and disease as it is acquired via resting-state functional magnetic resonance imaging (MRI), before focusing on how it is affected in various types of focal and generalized epilepsy. These findings support the potential use of DMN parameters as future biomarkers in epilepsy research, diagnosis, and management. |
| Databáze: | OpenAIRE |
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