GeNePy3D: a quantitative geometry python toolbox for bioimaging

Autor: Anatole Chessel, Minh-Son Phan
Přispěvatelé: Hub d'analyse d'images - Image Analysis Hub (Platform) (IAH), Institut Pasteur [Paris] (IP)-Université Paris Cité (UPCité), Laboratoire d'Optique et Biosciences (LOB), École polytechnique (X)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), This publication was supported by COST Action NEUBIAS (CA15124), funded by COST (European Cooperation in Science andTechnology., Phan, Minh Son
Jazyk: angličtina
Rok vydání: 2021
Předmět:
0301 basic medicine
Computer science
workflow
Framing (World Wide Web)
Bioimage informatics
MESH: Algorithms
computer.software_genre
General Biochemistry
Genetics and Molecular Biology

03 medical and health sciences
MESH: Software
0302 clinical medicine
Image Processing
Computer-Assisted

computational geometry
Animals
MESH: Animals
General Pharmacology
Toxicology and Pharmaceutics

MESH: Zebrafish
Spatial analysis
Zebrafish
Geometric data analysis
computer.programming_language
[INFO.INFO-BI] Computer Science [cs]/Bioinformatics [q-bio.QM]
General Immunology and Microbiology
Application programming interface
Software Tool Article
Programming language
quantitative geometry
Reproducibility of Results
Articles
General Medicine
Python (programming language)
Computational geometry
MESH: Image Processing
Computer-Assisted

Toolbox
bioimage informatics
python
MESH: Reproducibility of Results
030104 developmental biology
[INFO.INFO-BI]Computer Science [cs]/Bioinformatics [q-bio.QM]
computer
Algorithms
Software
030217 neurology & neurosurgery
Zdroj: F1000Research
F1000Research, 2021, ⟨10.12688/f1000research.27395.2⟩
ISSN: 2046-1402
Popis: La date de publication correspond à la deuxième version de l'article (Première version 26 novembre 2020); International audience; The advent of large-scale fluorescence and electronic microscopy techniques along with maturing image analysis is giving life sciences a deluge of geometrical objects in 2D/3D(+t) to deal with. These objects take the form of large scale, localised, precise, single cell, quantitative data such as cells’ positions, shapes, trajectories or lineages, axon traces in whole brains atlases or varied intracellular protein localisations, often in multiple experimental conditions. The data mining of those geometrical objects requires a variety of mathematical and computational tools of diverse accessibility and complexity. Here we present a new Python library for quantitative 3D geometry called GeNePy3D which helps handle and mine information and knowledge from geometric data, providing a unified application programming interface (API) to methods from several domains including computational geometry, scale space methods or spatial statistics. By framing this library as generically as possible, and by linking it to as many state-of-the-art reference algorithms and projects as needed, we help render those often specialist methods accessible to a larger community. We exemplify the usefulness of the GeNePy3D toolbox by re-analysing a recently published whole-brain zebrafish neuronal atlas, with other applications and examples available online. Along with an open source, documented and exemplified code, we release reusable containers to allow for convenient and wide usability and increased reproducibility.
Databáze: OpenAIRE