Calcium-binding protein in the developing rat cerebellum

Autor: Ch. Legrand, Monique Thomasset, Alain Rabié, C. O. Parkes, Marie-Claude Clavel
Rok vydání: 1983
Předmět:
Zdroj: Cell and Tissue Research. 233
ISSN: 1432-0878
0302-766X
Popis: Specific antibodies raised against a human 28 000 dalton cerebellar calcium-binding protein (CaBP) were used in an immunocytochemical study during development of the rat cerebellum. Both light and electron microscopy showed (1) that labelling was entirely restricted to the Purkinje cells, (2) that it appeared very early in Purkinje cell development, (3) that the entire cell was labelled from the tip of the smallest dendrites to the axonal terminals, and (4) that with increasing age, the immunoreaction appeared to be progressively restricted to the cell and organelle membranes.
Databáze: OpenAIRE