Estimation of intraocular lens position from full crystalline lens geometry: towards a new generation of intraocular lens power calculation formulas

Autor: Ignacio Jiménez-Alfaro, Sonia Durán-Poveda, Susana Marcos, Pablo Pérez-Merino, Eduardo Martinez-Enriquez
Přispěvatelé: Ministerio de Economía y Competitividad (España), European Commission, SCOAP
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Digital.CSIC. Repositorio Institucional del CSIC
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Scientific Reports
ISSN: 2045-2322
DOI: 10.1038/s41598-018-28272-6
Popis: 11 pags., 5 figs., 4 tabs. -- Open Access funded by Creative Commons Atribution Licence 4.0
In a cataract surgery, the opacified crystalline lens is replaced by an artificial intraocular lens (IOL). To optimize the visual quality after surgery, the intraocular lens to be implanted must be selected preoperatively for every individual patient. Different generations of formulas have been proposed for selecting the intraocular lens dioptric power as a function of its estimated postoperative position. However, very few formulas include crystalline lens information, in most cases only one-dimensional. The present study proposes a new formula to preoperatively estimate the postoperative IOL position (ELP) based on information of the 3-dimensional full shape of the crystalline lens, obtained from quantitative eye anterior segment optical coherence tomography imaging. Real patients were measured before and after cataract surgery (IOL implantation). The IOL position and the postoperative refraction estimation errors were calculated by subtracting the preoperative estimations from the actual values measured after surgery. The proposed ELP formula produced lower estimation errors for both parameters-ELP and refraction-than the predictions obtained with standard state-of-the-art methods, and opens new avenues to the development of new generation IOL power calculation formulas that improve refractive and visual outcomes.
The research leading to these results has received funding from the European Research Council under the European Union’s Seventh Framework Programme (FP7/2007-2013)/ERC Grant Agreement ERC-2011-AdG- 294099. This study has been also supported by Spanish government grants FIS2011-25637 and FIS2014-56643-R to S. Marcos. The funding organizations had no role in the design or conduct of this research.
Databáze: OpenAIRE
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