More Than 200 Genes Required for Methane Formation from H2 and CO2 and Energy Conservation Are Present in Methanothermobacter marburgensis and Methanothermobacter thermautotrophicus

Autor: Heiko Liesegang, Henning Seedorf, Gerhard Gottschalk, Meike Goenrich, Rudolf K. Thauer, Antje Wollherr, Anne-Kristin Kaster
Jazyk: angličtina
Rok vydání: 2011
Předmět:
Zdroj: Archaea, Vol 2011 (2011)
Archaea
Popis: The hydrogenotrophic methanogensMethanothermobacter marburgensisandMethanothermobacter thermautotrophicuscan easily be mass cultured. They have therefore been used almost exclusively to study the biochemistry of methanogenesis from H2and CO2, and the genomes of these two model organisms have been sequenced. The close relationship of the two organisms is reflected in their genomic architecture and coding potential. Within the 1,607 protein coding sequences (CDS) in common, we identified approximately 200 CDS required for the synthesis of the enzymes, coenzymes, and prosthetic groups involved in CO2reduction to methane and in coupling this process with the phosphorylation of ADP. Approximately 20 additional genes, such as those for the biosynthesis of F430and methanofuran and for the posttranslational modifications of the two methyl-coenzyme M reductases, remain to be identified.
Databáze: OpenAIRE