An MRI study of the corpus callosum in autism
Autor: | Stephan Arndt, James Bailey, Bonnie J. Ranson, Joseph Piven |
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Rok vydání: | 1997 |
Předmět: |
Adult
Male medicine.medical_specialty Adolescent Central nervous system Context (language use) Audiology Corpus callosum Corpus Callosum Sex Factors Neural Pathways mental disorders medicine Humans Autistic Disorder Child Intelligence Tests medicine.diagnostic_test Brain Magnetic resonance imaging Mean age medicine.disease Magnetic Resonance Imaging Developmental disorder Psychiatry and Mental health medicine.anatomical_structure nervous system Brain size Autism Female Psychology Neuroscience |
Zdroj: | American Journal of Psychiatry. 154:1051-1056 |
ISSN: | 1535-7228 0002-953X |
Popis: | Objective: The purpose of this study was to examine the size of subregions of the corpus callosum in autistic individuals. Method: The areas of three subregions (anterior, body, and posterior) of the corpus callosum were examined on midsagittal magnetic resonance images of 35 autistic subjects whose mean age was 18 years and 36 healthy comparison subjects matched on age and IQ. Results: After controlling for total brain volume, gender, and performance IQ, the authors detected a significantly smaller size of the body and posterior subregions of the corpus callosum in the autistic individuals. Conclusions: In the context of recent reports of increased brain size in autism, several possible mechanisms are considered in exploring the significance of a smaller relative size of the corpus callosum in autism. (Am J Psychiatry 1997; 154:1051‐1056) |
Databáze: | OpenAIRE |
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