| Autor: |
Jiarong Luo, Junjun Luo, Lei Deng, Minghui Yang, Xiang Chen |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Mikrochimica acta. 189(11) |
| ISSN: |
1436-5073 |
| Popis: |
A "signal-on" photoelectrochemical (PEC) immunosensor was successfully constructed for determination of human epidermal growth factor receptor 2 (HER2) based on organic-inorganic heterojunction Y6/CdS as photoactive material. Compared with single organic semiconductor, Y6, Y6/CdS exhibited higher photoelectric conversion efficiency due to the formation of heterojunction. In the presence of HER2, sandwich immune structure was formed between HER2 aptamer and anti-HER2 antibody (Ab) by specific recognition. The polydopamine (PDA) nanoparticles were used for signal amplification to enhance photocurrent intensity as PDA can act as electron donor to eliminate holes and promote electron-hole pairs separation. The developed PEC sensor displayed a wide detection range of 5-1000 pg mL |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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