Phenotypic drift in metastatic progression of breast cancer: A case report with histologically heterogeneous lesions that are clonally related

Autor:	Peter T. Simpson, Sunil R. Lakhani, Anna Sokolova, Jamie R. Kutasovic, Leonard Da Silva, Amy E. McCart Reed, Janani Jayanthan
Rok vydání:	2020
Předmět:	Medicine (General) Pathology medicine.medical_specialty recurrence comparative genomic hybridization Case Report Case Reports Gastric carcinoma 030204 cardiovascular system & hematology Metastasis 03 medical and health sciences R5-920 breast cancer 0302 clinical medicine Breast cancer medicine metastasis clonal progression skin and connective tissue diseases E‐cadherin Cadherin business.industry Stomach General Medicine medicine.disease Phenotype medicine.anatomical_structure 030220 oncology & carcinogenesis Invasive lobular carcinoma Medicine business Comparative genomic hybridization
Zdroj:	Clinical Case Reports Clinical Case Reports, Vol 8, Iss 12, Pp 2725-2731 (2020)
ISSN:	2050-0904
DOI:	10.1002/ccr3.3257
Popis:	Breast cancer metastasis to the stomach is rare; invasive lobular carcinoma has a predilection to spread to the gastrointestinal system and is morphologically similar to primary diffuse gastric carcinoma. This case highlights heterogeneous metastatic progression and that documentation of heterogeneity is important for informing future treatment strategies and prognostication.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c671d5fe9dcb35d88f69a2102ce97c8a https://doi.org/10.1002/ccr3.3257 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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