Surface engineering of macrophages with nucleic acid aptamers for the capture of circulating tumor cells

Autor:	Takeshi Mori, Rui Moriyama, Yasuhiko Iwasaki, Shunsuke Sugimoto
Rok vydání:	2015
Předmět:	Light Surface Properties Aptamer Cytological Techniques Immobilized Nucleic Acids Catalysis chemistry.chemical_compound Mice Circulating tumor cell Cell Line Tumor Materials Chemistry Cell Adhesion Animals Humans Lymphocytes Cell adhesion Cell Engineering Fluorescent Dyes Chemistry Macrophages Metals and Alloys Receptor Protein-Tyrosine Kinases Amino Sugars General Chemistry Adhesion Aptamers Nucleotide Neoplastic Cells Circulating N-Acetylneuraminic Acid Surfaces Coatings and Films Electronic Optical and Magnetic Materials Biochemistry Cell culture Cancer cell Ceramics and Composites Nucleic acid N-Acetylneuraminic acid
Zdroj:	Chemical communications (Cambridge, England). 51(98)
ISSN:	1364-548X
Popis:	In order to enhance the interactions between macrophages and cancer cells, thiol-terminated nucleic acid aptamers were immobilized on methacryloyl-functionalised carbohydrates of macrophages. The adhesion of cancer cells on the surface modified macrophages was significantly accelerated.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c661d2d42b664edd3009e3d6af52fefc https://pubmed.ncbi.nlm.nih.gov/26468496 Zobrazit plný text záznamu