Safety and efficacy of a bulk laxative containing senna versus lactulose in the treatment of chronic constipation in geriatric patients
| Autor: | P. Koistinen, I. Winblad, J. Salokannel, O. Kinnunen |
|---|---|
| Rok vydání: | 1993 |
| Předmět: |
Male
medicine.medical_specialty Senna medicine.medical_treatment Laxative Gastroenterology Lactulose Internal medicine medicine Humans Plantago Aged Pharmacology Geriatrics Aged 80 and over Chronic constipation biology Gastric emptying business.industry Cathartics Plant Extracts Plus senna Senna Extract General Medicine biology.organism_classification Drug Combinations Gastric Emptying Chronic Disease Female business Gastrointestinal Motility Bulk Laxatives Constipation medicine.drug |
| Zdroj: | Pharmacology. 47 |
| ISSN: | 0031-7012 |
| Popis: | Thirty geriatric long-stay patients aged 65-94 years (mean 81.8) participated in the trial the aim of which was to examine bulk laxative plus senna (Agiolax) in the treatment of chronic constipation using lactulose (Levolac) as a reference medicine. Bulk laxative plus senna (daily doses 14.8 g) produced more frequent (p0.05) bowel habits (4.5 vs. 2.2-1.9/week) than lactulose (daily doses 20.1 g). Both laxatives proved to be safe to use. Our study indicated bulk laxative plus senna to be more efficient in treating constipation in geriatric long-stay patients. |
| Databáze: | OpenAIRE |
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