Risk factors for mechanical ventilation in children with Guillain-Barré syndrome
| Autor: | Mei Li, Han-yu Luo, Li Wang, Siqi Hong, Li Jiang |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
Male medicine.medical_specialty Multivariate analysis Time Factors Physiology medicine.medical_treatment Neural Conduction Facial Muscles 030105 genetics & heredity Logistic regression Guillain-Barre Syndrome 03 medical and health sciences Cellular and Molecular Neuroscience 0302 clinical medicine Risk Factors Physiology (medical) Internal medicine medicine Humans Child Retrospective Studies Mechanical ventilation Univariate analysis Muscle Weakness Guillain-Barre syndrome business.industry Electrodiagnosis Infant Odds ratio medicine.disease Respiration Artificial Hospitalization Increased risk Bulbar weakness Child Preschool Female Neurology (clinical) business Respiratory Insufficiency 030217 neurology & neurosurgery |
| Zdroj: | MusclenerveREFERENCES. 62(2) |
| ISSN: | 1097-4598 |
| Popis: | Background We assessed clinical predictors of mechanical ventilation in children with Guillain-Barre syndrome (GBS) to help identify patients who require mechanical ventilation. Methods We retrospectively collected the clinical, laboratory, and electrophysiological data of 103 children with GBS. Patients were categorized into two groups based on the requirement for mechanical ventilation. Variables that were significantly different between the two groups in univariate analysis were analyzed by multivariate logistic regression models. Results Time from symptom onset to admission (P = .002), facial or bulbar weakness (P = .001), and axonal type (P = .005) were associated with mechanical ventilation in univariate analysis. In multivariate analysis, facial or bulbar weakness (odds ratio [OR], 7.936; P = .013) and axonal type (OR, 4.582; P = .022) were independent predictors for mechanical ventilation. Conclusions Facial or bulbar weakness and axonal type were associated with increased risk for mechanical ventilation in children with GBS. |
| Databáze: | OpenAIRE |
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