Growth hormone response to exercise in asthmatic and normal children
| Autor: | R. J. Dowdeswell, M. Plit, Seftel Hc, Vanessa R. Panz, I. Amirav, Barry I Joffe |
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| Rok vydání: | 1990 |
| Předmět: |
Male
medicine.medical_specialty Adolescent Growth hormone Reference Values Forced Expiratory Volume Internal medicine medicine Humans Asthmatic patient Child Exercise Asthma business.industry Air medicine.disease Growth hormone secretion Asthma Exercise-Induced Asthmatic children Endocrinology Growth Hormone Pediatrics Perinatology and Child Health Normal children Breathing Female Bronchoconstriction medicine.symptom business |
| Zdroj: | European Journal of Pediatrics. 149:443-446 |
| ISSN: | 1432-1076 0340-6199 |
| DOI: | 10.1007/bf02009670 |
| Popis: | Maximal growth hormone (GH) increments following exercise were compared in asthmatic (n = 14) and normal (n = 8) children. Exercise, which consisted of 6 min ergometer cycling while breathing cold dry (CD) air, induced asthma in all asthmatic patients but not in normal subjects. Baseline plasma GH levels were similar in both groups. Following exercise, however, asthmatic patients had significantly higher mean GH increments than normal subjects (14.8 vs 4.9 ng/ml, P less than 0.025). To evaluate the possible role of bronchoconstriction in the GH response all subjects exercised again, this time while breathing warm humid (WH) air. Despite the absence of exercise-induced asthma (EIA) while breathing WH air, asthmatic patients still had significantly higher mean GH increments than normal subjects (9.2 vs 2.3 ng/ml, P less than 0.05). We conclude that some asthmatic children show excessive GH secretion after exercise regardless of inspired air conditions or the development of EIA. |
| Databáze: | OpenAIRE |
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