Isotretinoin: Update on Controversial Issues
| Autor: | Joseph C. English, Noel Prevost |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
medicine.medical_specialty
Adolescent Inflammatory bowel disease Suicidal Ideation Pregnancy Risk Factors Acne Vulgaris medicine Humans Isotretinoin skin and connective tissue diseases Depression (differential diagnoses) Acne Depression business.industry Obstetrics and Gynecology General Medicine Inflammatory Bowel Diseases medicine.disease Dermatology Teratogens Pregnancy in Adolescence Pediatrics Perinatology and Child Health Female Dermatologic Agents business medicine.drug |
| Zdroj: | Journal of Pediatric and Adolescent Gynecology. 26:290-293 |
| ISSN: | 1083-3188 |
| Popis: | Acne vulgaris is a commonly seen dermatologic condition that plagues millions and can be very psychosocially disabling. Severe and recalcitrant acne is typically treated with isotretinoin. Isotretinoin is a synthetic vitamin A derivative that has been available since 1982. This therapeutic option has been the most effective at putting severe and recalcitrant acne vulgaris into remission. Despite its effectiveness, it has been associated with inflammatory bowel disease, depression, suicidality, and teratogenicity. We review the current literature on isotretinoin's role in inflammatory bowel disease, depression, and suicidality. In addition, we review whether or not the iPledge program has been successful at reducing pregnancy rates while on isotretinoin. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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