Fatal radiation hepatitis: a case report and review of the literature
| Autor: | Edward D. Crum, Visu Diwan, Suresh Kolli, Thomas R. Spitzer, Lee Schacter, John A. Maksem |
|---|---|
| Rok vydání: | 1986 |
| Předmět: |
Adult
medicine.medical_specialty medicine.medical_treatment Cystadenocarcinoma Autopsy Hysterectomy Hepatitis Sulfur colloid Ovarian carcinoma Antineoplastic Combined Chemotherapy Protocols medicine Humans Radiation Injuries Radionuclide Imaging Ovarian Neoplasms Chemotherapy Radiotherapy business.industry Obstetrics and Gynecology Radiotherapy Dosage medicine.disease Radiation therapy Radiation induced liver disease Oncology Technetium Tc 99m Sulfur Colloid Female Radiology business After treatment |
| Zdroj: | Gynecologic oncology. 24(3) |
| ISSN: | 0090-8258 |
| Popis: | A case of fatal radiation hepatitis occurring after treatment with 2200 rad given by the moving strip technique is presented. This fatality occurred in a 28-year-old woman with persistent ovarian carcinoma despite prolonged chemotherapy. Scans of the liver using computerized tomography, 99mTc sulfur colloid, and 99mTc diisopropyl iminodiacetic acid showed abnormalities only in sulfur colloid uptake and these resolved late in the course. Death was caused by progressive hepatic and renal failure. Postmortem examination showed changes typical of radiation hepatitis. Only 32 cases of radiation hepatitis have been previously reported and they are reviewed. The possible role of prolonged prior chemotherapy in enhancing sensitivity to radiotherapy is considered. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|