The selective amobarbital test in the anterior choroidal artery: Perfusion pattern assessed by intraarterial SPECT and prediction of postoperative verbal memory

Autor: Hasan Yilmaz, Margitta Seeck, Alan J. Pegna, Jean-Pierre Willi, Serge Vulliemoz, Laurent Spinelli, Jean-Marie Annoni, Theodor Landis
Rok vydání: 2008
Předmět:
Male
Amobarbital
medicine.medical_treatment
Neuropsychological Tests
Functional Laterality
Behavioral Neuroscience
Epilepsy
Hypnotics and Sedatives/administration & dosage
Hypnotics and Sedatives
Postoperative Period
skin and connective tissue diseases
Anterior temporal lobectomy
food and beverages
Electroencephalography
Middle Aged
Verbal Learning
Magnetic Resonance Imaging
Neurology
Evaluation Studies as Topic
Anesthesia
Female
Amobarbital/administration & dosage
medicine.symptom
Psychology
Anterior Temporal Lobectomy/methods
Perfusion
Carotid Artery
Internal
medicine.drug
Adult
Functional Laterality/drug effects/physiology
Adolescent
Amnesia
Tomography Emission-Computed Single-Photon
Temporal lobe
Memory
Predictive Value of Tests
medicine
Humans
Retrospective Studies
Tomography
Emission-Computed
Single-Photon
Carotid Artery Internal
Anterior Temporal Lobectomy
medicine.disease
Temporal Lobe/physiopathology/radionuclide imaging/surgery
eye diseases
ddc:616.8
Anterior choroidal artery
stomatognathic diseases
Epilepsy
Temporal Lobe
Memory/drug effects/physiology
Verbal Learning/drug effects/physiology
Neurology (clinical)
Verbal memory
Zdroj: Epilepsy & Behavior, Vol. 12, No 3 (2008) pp. 445-55
ISSN: 1525-5050
DOI: 10.1016/j.yebeh.2007.11.015
Popis: To screen for patients at risk for memory decline after temporal lobe epilepsy (TLE) surgery, selective amobarbital procedures, such as injection into the anterior choroidal artery (ACA-IAT), are sometimes used. We investigated the extent of the territory affected during ACA-IAT and its predictive value with respect to postoperative memory. Seventeen patients with TLE underwent ACA-IAT. In 9 of 17 patients, intraarterial SPECT co-registrated to MRI allowed delineation of amobarbital-perfused structures. Another subgroup of 9 of 17 patients underwent anterior temporal lobectomy. Verbal memory was tested pre- and postoperatively and during ACA-IAT. Major variations in the ACA-IAT perfusion pattern occurred and were not correlated with the verbal memory scores during ACA-IAT. Postoperatively, no patient experienced a severe verbal memory decline, but individual postoperative performance was not correlated with results during ACA-IAT. Our study suggests that ACA-IAT can be used to screen for severe postoperative amnesia in inconclusive cases, but cannot predict individual outcome, even when the perfusion pattern is taken into account.
Databáze: OpenAIRE
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