Aggressive hydration compared to standard hydration with lactated ringer’s solution for prevention of post endoscopic retrograde cholangiopancreatography pancreatitis
Autor: | Ying-Kang Xie, Ze-Kun Jiang, Rong-Chang Wang, Jing-Song Chen |
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Rok vydání: | 2020 |
Předmět: |
Abdominal pain
Ringer's Lactate Protective Agents Lower risk 03 medical and health sciences 0302 clinical medicine Odds Ratio medicine Humans Hyperamylasemia Randomized Controlled Trials as Topic Cholangiopancreatography Endoscopic Retrograde Endoscopic retrograde cholangiopancreatography medicine.diagnostic_test business.industry Incidence Odds ratio medicine.disease Abdominal Pain Pancreatitis 030220 oncology & carcinogenesis Anesthesia 030211 gastroenterology & hepatology Surgery Ringer's solution medicine.symptom business Abdominal surgery |
Zdroj: | Surgical Endoscopy. 35:1126-1137 |
ISSN: | 1432-2218 0930-2794 |
Popis: | Previous studies have suggested that aggressive hydration with lactated ringer solution are one of the protective factors in preventing post endoscopic retrograde cholangiopancreatography (post-ERCP). We conducted a systematic review and meta-analysis to examine the efficacy aggressive hydration with lactated Ringer solution in preventing PEP. All published and unpublished articles on aggressive hydration with lactated ringer solution in those underwent ERCP procedure for any reasons were screened for eligibility. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines were followed. This paper doesn’t need the IRB approval. Seven RCTs met the inclusion criteria. Meta-analysis indicates that aggressive hydration with lactated Ringer solution were associated with lower PEP rate.[odds ratio (OR) 0.29; 95% confidence interval (CI) 0.18–0.48]; lower incidence of hyperamylasemia (OR 0.49; 95% CI 0.35, 0.69) and lower risk of pain (OR 0.28; 95% CI 0.10–0.81). The association between aggressive hydration with lactated Ringer solution and incidence of moderate severity PEP were unclear (OR 0.57; 95% CI 0.22, 1.45). Sensitivity analyses also showed that omitting 1 study from analysis of PEP rate could reduce the heterogeneity but did not change the conclusion of this meta-analysis. A cumulating meta-analysis was performed statistically which showed a stable result of overall incidence of PEP. Aggressive hydration with lactated Ringer solution was a protective factor in reducing the overall incidence of PEP, hyperamylasemia and risk of abdominal pain. |
Databáze: | OpenAIRE |
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