Cytotoxic activity of peripheral blood platelets and mononuclears in cancer patients and healthy donors

Autor:	S. N. Bykovskaya, M. V. Kiselevskii, A. R. Tuguz, D. V. Komov, A. M. Buntsevich, I. G. Komarov, E. M. Roschin, V. A. Normantovich, B. E. Polotskii, T. S. Golubeva
Rok vydání:	1996
Předmět:	business.industry medicine.medical_treatment Killer activity Pulmonary adenocarcinoma General Medicine General Biochemistry Genetics and Molecular Biology Peripheral blood Radiation therapy Immunology Continuous cell line Medicine Cytotoxic T cell Platelet business Cytotoxicity
Zdroj:	Scopus-Elsevier
ISSN:	1573-8221 0007-4888
DOI:	10.1007/bf02446630
Popis:	The cytotoxic activity of peripheral blood platelets and mononuclears from 82 patients with cancer, 9 with diseases other than cancer, and 18 healthy donors towards a continuous cell line of pulmonary adenocarcinoma was studied. There were no appreciable differences in the killer activity of platelets in cancer patients (32±3.5%), patients with diseases other than cancer (33±8.1%), and healthy donors (30±6.7%). In contrast to platelets, mononuclears of cancer patients possessed a higher cytotoxicity than mononuclears of healthy donors. The cytotoxicity of platelets of cancer patients was found to reliably drop in cases with disseminated metastases and after polychemo-and radiotherapy.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6289c44891eb4baa0c3f91ff2217c12 https://doi.org/10.1007/bf02446630 Zobrazit plný text záznamu Full text from SpringerLink