Point-of-care umbilical arterial lactate and newborn outcomes in a low resource setting: cohort study
| Autor: | Luis Aaron Gadama, George Kassim Chilinda, William Stones |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Adult
Malawi medicine.medical_specialty Referral Newborn care Point-of-Care Systems 030231 tropical medicine Neonatal death lcsh:Medicine Umbilical Arteries General Biochemistry Genetics and Molecular Biology Cohort Studies Fetal distress 03 medical and health sciences 0302 clinical medicine Pregnancy Interquartile range medicine Humans Hyperlactatemia Lactic Acid lcsh:Science (General) lcsh:QH301-705.5 Asphyxia Asphyxia Neonatorum Rapid diagnostic test 030219 obstetrics & reproductive medicine Obstetrics business.industry Birth asphyxia lcsh:R Infant Newborn General Medicine medicine.disease Malaria Research Note lcsh:Biology (General) Apgar Score Female Apgar score RG medicine.symptom business Cohort study lcsh:Q1-390 |
| Zdroj: | BMC Research Notes, Vol 11, Iss 1, Pp 1-5 (2018) BMC Research Notes |
| ISSN: | 1756-0500 |
| DOI: | 10.1186/s13104-018-3598-9 |
| Popis: | Objective Birth asphyxia contributes substantially to the burden of intrapartum stillbirth and neonatal mortality in resource limited countries. We investigated clinical correlates and neonatal outcomes of lactate analysis of umbilical arterial cord blood in a large referral maternity unit in Malawi using a point-of-care test (Lactate Xpress, Nova Biomedical, Runcorn, UK) and examined maternal and neonatal characteristics and outcomes. Results There were 389 live births and 12 intrapartum stillbirths during the study. The median umbilical arterial lactate concentration was 3.4 mmol/L (interquartile range 2.6–4.9). Umbilical arterial lactate concentrations among the 45 babies admitted for special neonatal care were above 5 mmol/L in 16/45 (36%) of cases, with no fatality below 13 mmol/L. A positive malaria rapid diagnostic test was associated with hyperlactatemia (p |
| Databáze: | OpenAIRE |
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