Hyperbaric Oxygen Therapy as Adjuvant Treatment for Idiopathic Sudden Sensorineural Hearing Loss after Failure of Systemic Steroids

Autor: Satoru Takebayashi, Kenichi Sugiyama, Goro Takahashi, Hiroyuki Mineta, Seiji Hosokawa, Kumiko Hosokawa, Yuichi Hashimoto
Rok vydání: 2017
Předmět:
Male
Hydrocortisone
Physiology
medicine.medical_treatment
Administration
Oral
Comorbidity
0302 clinical medicine
Vertigo
Child
030223 otorhinolaryngology
Aged
80 and over
Hyperbaric Oxygenation
biology
Smoking
Middle Aged
Combined Modality Therapy
Sensory Systems
Treatment Outcome
Hearing level
030220 oncology & carcinogenesis
Anesthesia
Sudden sensorineural hearing loss
Hypertension
Administration
Intravenous
Female
Sensorineural hearing loss
Adjuvant
Adult
Adolescent
Hearing Loss
Sensorineural
Prednisolone
Young Adult
03 medical and health sciences
Speech and Hearing
Hyperbaric oxygen
Audiometry
Diabetes mellitus
Diabetes Mellitus
medicine
Humans
Glucocorticoids
Aged
Retrospective Studies
business.industry
Hearing Loss
Sudden
biology.organism_classification
medicine.disease
Otorhinolaryngology
Case-Control Studies
Complication
business
Zdroj: Audiology and Neurotology. 22:9-14
ISSN: 1421-9700
1420-3030
DOI: 10.1159/000464096
Popis: We evaluated the outcomes of and prognostic factors for idiopathic sudden sensorineural hearing loss (ISSNHL) treated with adjuvant hyperbaric oxygen therapy (HBOT). A retrospective review of clinical data was performed for 167 patients with ISSNHL who failed to respond to systemic steroids and were treated by adjuvant HBOT at Shizuoka Saiseikai General Hospital. We analysed the clinical outcomes, the averaged 5-frequency hearing level after systemic steroids, patient age, the interval between post-steroids and pre-HBOT, vertigo as a complication, the presence of diabetes mellitus, smoking history, and hypertension. Overall, after HBOT, complete recovery occurred in 16 (9.6%) of the patients, with definite improvement in 16 (9.6%) and slight improvement in 45 (26.9%). The overall rate of hearing improvement was higher in the study group (77/167 cases, 46.1%) than in the control group (52/160 cases, 32.5%; p = 0.021). If performed appropriately, HBOT should be able to improve hearing in many cases unresponsive to initial therapy.
Databáze: OpenAIRE
Externí odkaz: