Misinterpretation of the chest x ray as a factor in the delayed diagnosis of lung cancer
| Autor: | N Kennan, M A Greenstone, P M Turkington |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2002 |
| Předmět: |
Thorax
medicine.medical_specialty Lung Neoplasms Time Factors Radiography Interquartile range medicine Humans Diagnostic Errors Lung cancer Survival rate False Negative Reactions Aged Retrospective Studies business.industry Respiratory disease Retrospective cohort study General Medicine Middle Aged medicine.disease Survival Rate Original Article Radiology Abnormality business |
| Popis: | All patients in 1997 with a histologically proved diagnosis of lung cancer in Castle Hill Hospital in whom a full set of case notes and x rays could be retrieved were studied. All previous chest x rays were reviewed by a consultant chest physician and a radiologist, who were blinded to the eventual site of the lesion and the point at which a suspicious abnormality first appeared. Case notes were inspected to clarify the cause of any error. Fifty eight patients were eligible, 28 of whom had previous chest x rays. Of these 14 were found to be abnormal. A significant difference (p=0.007) in time from diagnosis to death was found between those with a missed abnormality, median (interquartile range, IQR) 105 (55–219) days and those with no previous abnormality, median (IQR) 260 (137–512) days. In the 14 in whom the diagnosis was missed the median (IQR) delay from first abnormal chest x ray to the eventual diagnostic x ray was 101 (48–339) days. A significant difference (p=0.001) was also found between the median (IQR) time from first abnormal chest x ray to start of treatment between those with missed abnormalities, 155 (115–376) days, and those with no previous abnormality on chest x ray, 51 (44–77) days. The most common reason (47%) for the diagnosis to be missed was failure of the radiologist reporting the x ray to recognise the abnormality. It is not unusual to find previous significant radiological abnormalities in patients in whom a diagnosis of lung cancer is later made. This leads to a diagnostic delay which has a significant effect on time to initiation of treatment and palliation of symptoms, although not necessarily to eventual outcome. |
| Databáze: | OpenAIRE |
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