Quantitative muscle ultrasonography in amyotrophic lateral sclerosis
| Autor: | Ilse M.P. Arts, H. Jurgen Schelhaas, Sebastiaan Overeem, Henny M.H.A. Janssen, Frank G. van Rooij, Machiel J. Zwarts, Sigrid Pillen |
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| Rok vydání: | 2008 |
| Předmět: |
Adult
Male Acoustics and Ultrasonics Biophysics Fasciculation Biceps Neuromuscular ultrasound Forearm medicine Perception and Action [DCN 1] Humans Radiology Nuclear Medicine and imaging Amyotrophic lateral sclerosis Muscle Skeletal Aged Ultrasonography Aged 80 and over Radiological and Ultrasound Technology business.industry Amyotrophic Lateral Sclerosis Skeletal muscle Anatomy Middle Aged medicine.disease Fibrosis Neuromuscular development and genetic disorders [UMCN 3.1] medicine.anatomical_structure Female Brachialis medicine.symptom business Functional Neurogenomics [DCN 2] |
| Zdroj: | Ultrasound in Medicine and Biology, 34, 3, pp. 354-61 Ultrasound in Medicine and Biology, 34, 354-61 |
| ISSN: | 0301-5629 |
| DOI: | 10.1016/j.ultrasmedbio.2007.08.013 |
| Popis: | Contains fulltext : 71289.pdf (Publisher’s version ) (Closed access) In this study, we examined whether quantitative muscle ultrasonography can detect structural muscle changes in early-stage amyotrophic lateral sclerosis (ALS). Bilateral transverse scans were made of five muscles or muscle groups (sternocleidomastoid, biceps brachii/brachialis, forearm flexor group, quadriceps femoris and anterior tibialis muscles) in 48 patients with ALS. Twenty-five patients were also screened for fasciculations. Quantitative analysis revealed a significant increase in echo intensity in all muscles and a decrease in muscle thickness of the biceps brachii, forearm flexors and quadriceps femoris on both sides. Fasciculations were easy to detect in multiple muscles of all screened patients except one. We conclude that quantitative ultrasonography can be used to detect muscle changes caused by ALS in an early phase of the disease. (E-mail: m.zwarts@neuro.umcn.nl). |
| Databáze: | OpenAIRE |
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