Hormonal Effects on Breast Density, Fibroglandular Tissue, and Background Parenchymal Enhancement
| Autor: | Samantha L. Heller, Amy N. Melsaether, Yiming Gao, Linda Moy, Leng Leng Young Lin |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Oncology
medicine.medical_specialty Hormone Replacement Therapy medicine.medical_treatment Breast Neoplasms 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Breast cancer Internal medicine Parenchyma medicine Humans Mammography Radiology Nuclear Medicine and imaging Breast Breast density skin and connective tissue diseases Breast Density medicine.diagnostic_test business.industry Magnetic resonance imaging Hormone replacement therapy (menopause) medicine.disease Magnetic Resonance Imaging Hormones Review article body regions 030220 oncology & carcinogenesis Female business Hormone |
| Zdroj: | RadioGraphics. 38:983-996 |
| ISSN: | 1527-1323 0271-5333 |
| Popis: | Breast density, fibroglandular tissue, and background parenchymal enhancement (BPE) are recognized independent biomarkers for breast cancer risk. For this reason, reproducibility and consistency in objective assessment of these parameters at mammography (breast density) and at magnetic resonance imaging (fibroglandular tissue and BPE) are clinically relevant. However, breast density, fibroglandular tissue, and BPE are manifestations of dynamic physiologic processes and may change in response to both endogenous and exogenous hormonal stimulation. It is therefore important for the radiologist to recognize settings in which hormonal stimulation may alter the appearance of these biomarkers at imaging and to appreciate how such changes may affect risk assessment, cancer detection, and even prognosis. The purpose of this review article is therefore to review key features and means of evaluating breast density, fibroglandular tissue, and BPE at imaging; to detail how endogenous and exogenous hormonal stimuli may affect breast density, fibroglandular tissue, and BPE, potentially affecting radiologic interpretation; and, finally, to provide an update regarding current hormone treatment guidelines and indications that may result in imaging changes through hormone modulation. ©RSNA, 2018. |
| Databáze: | OpenAIRE |
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