Effect of udenafil administration on postmicturition dribbling in men: a prospective, multicenter, double-blind, placebo-controlled, randomized clinical study
| Autor: | Seong Ho Lee, Dae Yul Yang, Jin Seon Cho, Jun Hyun Han, Sung Tae Cho, Cheol Young Oh, Min Soo Choo, Won Ki Lee, Hyun Cheol Jeong, Tae Young Shin, Young Gu Lee, Kyungtae Ko |
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| Rok vydání: | 2019 |
| Předmět: |
Male
medicine.medical_specialty 030232 urology & nephrology Urology Prostatic Hyperplasia 030209 endocrinology & metabolism Placebo Double blind Clinical study 03 medical and health sciences 0302 clinical medicine Urinary Leakage Double-Blind Method Lower urinary tract symptoms medicine Humans Normal voiding Prospective Studies Udenafil Sulfonamides business.industry Middle Aged Phosphodiesterase 5 Inhibitors medicine.disease Pyrimidines Treatment Outcome Geriatrics and Gerontology business medicine.drug |
| Zdroj: | The aging male : the official journal of the International Society for the Study of the Aging Male. 23(5) |
| ISSN: | 1473-0790 |
| Popis: | Postmicturition dribbling (PMD) is a stressful symptom in middle-aged men characterized by urinary leakage after the completion of normal voiding. Appropriate treatments have not yet been introduced. This study assessed the efficacy of treatment of PMD with 75 mg udenafil daily.The study included 138 men with regular sexual lifestyles. The Hallym PMD questionnaire (HPMDQ) was used to assess PMD symptoms. After all basic examinations, patients were randomly assigned to either udenafil or placebo. Patients completed the surveys, uroflowmetry (UFM), a bladder scan, and the paper test during the follow-up visit.The mean age of the patients was 57.6 years. PMD with one of every three urinations was experienced by 59 patients (42.8%), whereas 45 patients (32.6%) experienced PMD with two of every three urinations. PMD with every urination was experienced by 34 patients (24.6%). More than half of the patients (89 patients, 65.4%) indicated that persistent PMD symptoms would likely result in moderate to severe discomfort in their daily activities. As time passed, the udenafil group showed significant improvement in PMD symptoms (Udenafil 75 mg once daily can be an effective treatment for patients with PMD symptoms. |
| Databáze: | OpenAIRE |
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