Genomic prediction for beef fatty acid profile in Nellore cattle

Autor: Rafael Medeiros de Oliveira Silva, Lenise Freitas Mueller, Mariana Piatto Berton, Rafael Lara Tonussi, Rafael Espigolan, Daniel Gustavo Mansan Gordo, Adrielle Matias Ferrinho, Bianca Ferreira Olivieri, F. L. B. Feitosa, Gerardo Alves Fernandes Júnior, Ana Fabrícia Braga Magalhães, Angélica Simone Cravo Pereira, Elisa Peripoli, Marcos Vinícius Antunes de Lemos, Humberto Tonhati, Joyce de Jesus Mangini Furlan, Fernando Baldi, Henrique Nunes de Oliveira, Lucia Galvão de Albuquerque, Carolyn Aboujaoude, Tiago Bresolin, Hermenegildo Lucas Justino Chiaia
Přispěvatelé: Universidade Estadual Paulista (Unesp), Universidade de São Paulo (USP)
Rok vydání: 2017
Předmět:
0301 basic medicine
Longissimus thoracis muscle
Male
Meat
Nellore cattle
Muscle Proteins
Bos indicus
Context (language use)
QUALIDADE DOS ALIMENTOS
Biology
Polymorphism
Single Nucleotide

Cross-validation
Fatty Acids
Monounsaturated

03 medical and health sciences
Animal science
Fatty Acids
Omega-6

Fatty Acids
Omega-3

SNP
Animals
Humans
Meat quality
Selection
Genetic

Muscle
Skeletal

chemistry.chemical_classification
Genomic selection
Models
Genetic

business.industry
Fatty Acids
0402 animal and dairy science
Fatty acid
Bayes Theorem
04 agricultural and veterinary sciences
Genomics
040201 dairy & animal science
Biotechnology
Lipid profile
030104 developmental biology
chemistry
Feedlot
Feasibility Studies
Cattle
business
Nutritive Value
Brazil
Polyunsaturated fatty acid
Animals
Inbred Strains

Food Science
Zdroj: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Popis: Made available in DSpace on 2018-12-11T17:31:30Z (GMT). No. of bitstreams: 0 Previous issue date: 2017-06-01 Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) The objective of this study was to compare SNP-BLUP, BayesCπ, BayesC and Bayesian Lasso methodologies to predict the direct genomic value for saturated, monounsaturated, and polyunsaturated fatty acid profile, omega 3 and 6 in the Longissimus thoracis muscle of Nellore cattle finished in feedlot. A total of 963 Nellore bulls with phenotype for fatty acid profiles, were genotyped using the Illumina BovineHD BeadChip (Illumina, San Diego, CA) with 777,962 SNP. The predictive ability was evaluated using cross validation. To compare the methodologies, the correlation between DGV and pseudo-phenotypes was calculated. The accuracy varied from − 0.40 to 0.62. Our results indicate that none of the methods excelled in terms of accuracy, however, the SNP-BLUP method allows obtaining less biased genomic evaluations, thereby; this method is more feasible when taking into account the analyses' operating cost. Despite the lowest bias observed for EBV, the adjusted phenotype is the preferred pseudophenotype considering the genomic prediction accuracies regarding the context of the present study. Faculdade de Ciências Agrárias e Veterinárias UNESP Jaboticabal Faculdade de Medicina Veterinária e Zootecnia USP Pirassununga Faculdade de Zootecnia e Engenharia de Alimentos USP Pirassununga Faculdade de Ciências Agrárias e Veterinárias UNESP Jaboticabal FAPESP: #2009/16118-5 FAPESP: (#2011/2141-0
Databáze: OpenAIRE