MR imaging of spleen in beta-thalassemia major
| Autor: | Tomas Maris, Artemis Vasiliadou, Alex Papadakis, Olympia Papakonstantinou, Nicholas Gourtsoyiannis, Eleni E. Drakonaki |
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| Rok vydání: | 2015 |
| Předmět: |
Adult
Male medicine.medical_specialty Iron Overload Iron kinetics Adolescent Urology Thalassemia Iron deposition Spleen BETA THALASSEMIA MAJOR Young Adult Internal medicine medicine Humans Radiology Nuclear Medicine and imaging Child Retrospective Studies Splenic Diseases Radiological and Ultrasound Technology business.industry beta-Thalassemia Gastroenterology Organ Size General Medicine Hepatology medicine.disease Magnetic Resonance Imaging Mr imaging medicine.anatomical_structure Splenomegaly Female Radiology Siderosis Nuclear medicine business |
| Zdroj: | Abdominal Imaging. 40:2777-2782 |
| ISSN: | 1432-0509 0942-8925 |
| DOI: | 10.1007/s00261-015-0461-5 |
| Popis: | Splenomegaly and splenic siderosis are well-known findings in beta-thalassemia major. We explored the relation between splenic size, splenic and hepatic siderosis in transfusion-dependent beta-thalassemic patients, assessed by MR imaging. Abdominal MR imaging studies of 47 consecutive thalassemic patients and 10 healthy subjects, used as controls, were retrospectively reviewed. The signal intensity ratios of spleen and liver to the right paraspinous muscle (S/M, L/M, respectively) were calculated on T1, intermediate, and T2*-weighted gradient-echo sequences, splenic volume was estimated on axial images and serum ferritin levels were recorded. Decreased S/M on all MR sequences was displayed in 36 patients. Six patients presented with normal S/M on all MR sequences and 5 patients displayed splenic hypointensity only on T2* sequence. No correlation between S/M and L/M was found whereas both L/M and S/M correlated with serum ferritin (P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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