Enantioselective Palladium-Catalyzed [3 + 2] Cycloadditions of Trimethylenemethane with Nitroalkenes
| Autor: | Dustin A. Bringley, Pamela S. Seng, Barry M. Trost |
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| Rok vydání: | 2011 |
| Předmět: |
Models
Molecular Molecular Structure Nitrogen Organic Chemistry Trimethylenemethane Enantioselective synthesis chemistry.chemical_element Stereoisomerism Alkenes Ligands Biochemistry Catalysis Article Cycloaddition chemistry.chemical_compound chemistry Cyclization Yield (chemistry) Organic chemistry Physical and Theoretical Chemistry Methane Palladium |
| Zdroj: | Organic Letters. 14:234-237 |
| ISSN: | 1523-7052 1523-7060 |
| Popis: | Nitroalkenes readily undergo palladium-catalyzed [3 + 2] cycloaddition with trimethylenemethane to generate nitrocyclopentanes in excellent yield and enantioselectivity. Furthermore, the products thus formed are highly versatile synthetic intermediates and provide convenient access to both cyclopentylamines and cyclopentenones. |
| Databáze: | OpenAIRE |
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