Diagnostic value of diffusion weighted MRI and ADC in differential diagnosis of cavernous hemangioma of the liver

Autor: Ilker Oz, Ebru Unlu, Elif Aktas, İlker Ünal, Özlem Tokgöz, Emrah Caglar, Ismail Serifoglu
Přispěvatelé: Çukurova Üniversitesi, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Ünal, İlker, Çukurova Üniversitesi, Zonguldak Bülent Ecevit Üniversitesi
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: African Health Sciences; Vol 16, No 1 (2016); 227-233
ISSN: 1680-6905
Popis: WOS: 000378847700030
PubMed: 27358636
Aims: To investigate the use of diffusion weighted magnetic resonance imaging (DWI) and the apparent diffusion coefficient (ADC) values in the diagnosis of hemangioma. Materials and methods: The study population consisted of 72 patients with liver masses larger than 1 cm (72 focal lesions). DWI examination with a b value of 600 s/mm(2) was carried out for all patients. After DWI examination, an ADC map was created and ADC values were measured for 72 liver masses and normal liver tissue (control group). The average ADC values of normal liver tissue and focal liver lesions, the "cut-off " ADC values, and the diagnostic sensitivity and specificity of the ADC map in diagnosing hemangioma, benign and malignant lesions were researched. Results: Of the 72 liver masses, 51 were benign and 21 were malignant. Benign lesions comprised 38 hemangiomas and 13 simple cysts. Malignant lesions comprised 9 hepatocellular carcinomas, and 12 metastases. The highest ADC values were measured for cysts (3.782 +/- 0.53x10(-3) mm(2)/s) and hemangiomas (2.705 +/- 0.63x10(-3) mm(2)/s). The average ADC value of hemangiomas was significantly higher than malignant lesions and the normal control group (p
Databáze: OpenAIRE